Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2024 Oct 24;16(10):e72284.
doi: 10.7759/cureus.72284. eCollection 2024 Oct.

Diabetic Striatopathy: A Case Report of Two Distinct Presentations in Elderly Patients

Affiliations
Case Reports

Diabetic Striatopathy: A Case Report of Two Distinct Presentations in Elderly Patients

Paula A Calvo et al. Cureus. .

Abstract

Movement disorders associated with diabetes mellitus (DM) are rare. The diagnosis of diabetic striatopathy (DS) is based on the presence of a triad characterized by hyperglycemia, hemiballismus/chorea, and hypersignal of the basal ganglia on T1-weighted MRI. In most cases, treatment involves glycemic control. DS should be considered a differential diagnosis in episodes of extrapyramidal movements, especially when associated with hyperglycemia in the elderly. In this paper, we present two cases of DS.

Keywords: ballism; chorea; diabetic; hyperglycemia; striatopathy.

PubMed Disclaimer

Conflict of interest statement

Human subjects: Consent for treatment and open access publication was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. MRI of Patient 1 showing T1 hypersignal in the lenticular nuclei.
Figure 2
Figure 2. MRI of Patient 2 showing hyposignality in the corpus striatum in FLAIR T2.
FLAIR: fluid-attenuated inversion recovery.

References

    1. Diabetic striatopathy: an updated overview of current knowledge and future perspectives. Arecco A, Ottaviani S, Boschetti M, Renzetti P, Marinelli L. J Endocrinol Invest. 2024;47:1–15. - PMC - PubMed
    1. Some observations on hemiballismus. Bedwell SF. Neurology. 1960;10:619–622. - PubMed
    1. "Diabetic striatopathy": clinical presentations, controversy, pathogenesis, treatments, and outcomes. Chua CB, Sun CK, Hsu CW, Tai YC, Liang CY, Tsai IT. Sci Rep. 2020;10:1594. - PMC - PubMed
    1. Diabetic striatopathy. Chutpiboonwat P, Chutinet A, Tontiwutikul B, Snabboon T. Acta Med Port. 2021;34:874–875. - PubMed
    1. "Diabetic striatopathy" and ketoacidosis: report of two cases and review of literature. Das L, Pal R, Dutta P, Bhansali A. https://doi.org/10.1016/j.diabres.2017.03.008. Diabetes Res Clin Pract. 2017;128:1–5. - PubMed

Publication types

LinkOut - more resources