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Review
. 2024 Nov 26;26(1):10.
doi: 10.1007/s10048-024-00791-7.

Nutrigenomics and neurological disorders: exploring diet-brain interactions for cognitive health

Atifa Waheed  1 , Maliha Ghaffar  2 , Samavia Mustafa  1 , Anam Abbas  1 , Sana Khan  1 , Ahmad Waheed  3 , Hina Naz  3
Affiliations
Review

Nutrigenomics and neurological disorders: exploring diet-brain interactions for cognitive health

Atifa Waheed et al. Neurogenetics. .

Abstract

This review article investigates the intricate relationship between nutrigenomics and neurological disorders, highlighting how genetic variations affect an individual's response to nutrients. The study delves into the role of diet-related oxidative stress and the gut-brain axis in the progression and management of brain disorders such as Parkinson's disease, Alzheimer's disease, epilepsy, stroke, migraines, and depression. The review encompasses various clinical trials and introduces new trends and techniques, including omics and artificial intelligence, in identifying and managing neurological disorders. The main findings emphasize that personalized diet recommendations, tailored to an individual's genetic makeup, can significantly improve cognitive health and manage neurological conditions. The study concludes that further research in the field of nutrigenomics is essential to advancing personalized nutrition strategies for better neurological functioning, ultimately linking diet, genes, and brain health.

Keywords: Cognitive health; Gut microbiota; Neurological disorders; Nutrigenomics.

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Conflict of interest statement

Declarations. Ethical approval: Not applicable. Consent, Data, Material and/or code availability: Not applicable. Competing interests: The authors declare no competing interests.

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