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Review
. 2024 Dec-Dec;16(23-24):1261-1278.
doi: 10.1080/17576180.2024.2415779. Epub 2024 Nov 26.

Iron oxide nanozymes as versatile analytical tools: an overview of their application as detection technique

Affiliations
Review

Iron oxide nanozymes as versatile analytical tools: an overview of their application as detection technique

Rana Said et al. Bioanalysis. 2024 Dec-Dec.

Abstract

Iron oxide nanozymes (IONzymes) have become fundamental components in various analyte detection methodologies such as colorimetric, electrochemistry, fluorescence and luminescence. Their tunability, stability and the possibility of modification, alongside their ability to mimic the catalytic properties of natural enzymes like peroxidase, render them invaluable in analytical chemistry. This review explores the diverse applications of IONzymes across analytical chemistry, with a particular highlighting on their roles in different detection techniques and their potential in biomedical and diagnostic applications. This information would be valuable for researchers and practitioners in the fields of analytical chemistry, biochemistry, biotechnology and materials science who are interested in applying IONzymes in their work. In essence, this review article on iron oxide nanozymes in analytical chemistry would serve as a valuable resource for researchers, educators and industry professionals, offering insights, guidance and inspiration for further study and application of this promising class of nanomaterials.

Keywords: biosensors; biosynthesis; chemical synthesis; iron oxide nanozymes (IONzymes); magnatic nanoparticles; nanocatalyst.

Plain language summary

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Conflict of interest statement

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

References

    1. Wang X, Guo W, Hu Y, et al. . Nanozymes: next wave of artificial enzymes. Germany: SpringerBerlin Heidelberg; 2016. doi:10.1007/978-3-662-53068-9 - DOI
    1. Ghazzy A, Nsairat H, Said R, et al. . Magnetic iron oxide-based nanozymes: from synthesis to application. Nanoscale Advances. 2024;6:1611–1642. doi:10.1039/D3NA00903C - DOI - PMC - PubMed
    2. •• This recent study provides an up-to-date discussion on the synthesis and application of magnetic iron oxide nanozymes, directly aligning with the detection applications discussed in this paper.

    1. Jiangjiexing W, Hui W. Efficient design strategies for nanozymes. Progr Chem. 2021;33(1):42.
    1. Wen S, Ma X, Liu H, et al. . Accurate monitoring platform for the surface catalysis of nanozyme validated by surface-enhanced Raman-kinetics model. Anal Chem. 2020;92(17):11763–11770. doi:10.1021/acs.analchem.0c01886 - DOI - PubMed
    1. Li S, Zhang Y, Wang Q, et al. . Nanozyme-enabled analytical chemistry. Anal Chem. 2021;94(1):312–323. doi:10.1021/acs.analchem.1c04492 - DOI - PubMed
    2. • This reference is of considerable interest as it focuses on the use of nanozymes in analytical chemistry, a core theme of this paper.

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