Personalized Medicine: Unraveling the Potential of Diamine Oxidase Deficiency
- PMID: 39597941
- PMCID: PMC11595060
- DOI: 10.3390/jcm13226797
Personalized Medicine: Unraveling the Potential of Diamine Oxidase Deficiency
Abstract
The Special Issue Diamine Oxidase Deficiency: Prevalence, consequences, and solutions brings together a series of groundbreaking studies that explore the role of four single-nucleotide polymorphisms (SNPs) (rs10156191, rs1049742, rs1049793, and rs2052129) of the Diamine Oxidase (DAO) across various medical conditions, with a special focus on its influence on histamine metabolism [...].
Conflict of interest statement
In the last 24 months, H.B.F. has received lecture fees from Takeda, laboratories Rubio. He received funding from DR Healthcare-AB Biotek HNH. He is co-Founder of Haglaia Solutions (
Similar articles
-
Prevalence of Genetic Diamine Oxidase (DAO) Deficiency in Female Patients with Fibromyalgia in Spain.Biomedicines. 2023 Feb 22;11(3):660. doi: 10.3390/biomedicines11030660. Biomedicines. 2023. PMID: 36979637 Free PMC article.
-
Association of single nucleotide polymorphisms in the diamine oxidase gene with diamine oxidase serum activities.Allergy. 2011 Jul;66(7):893-902. doi: 10.1111/j.1398-9995.2011.02548.x. Epub 2011 Apr 13. Allergy. 2011. PMID: 21488903
-
Prevalence of Diamine Oxidase Enzyme (DAO) Deficiency in Subjects with Insomnia-Related Symptoms.J Clin Med. 2024 Aug 6;13(16):4583. doi: 10.3390/jcm13164583. J Clin Med. 2024. PMID: 39200725 Free PMC article.
-
Histamine pharmacogenomics.Pharmacogenomics. 2009 May;10(5):867-83. doi: 10.2217/pgs.09.26. Pharmacogenomics. 2009. PMID: 19450133 Review.
-
Putrescine metabolism and the study of diamine oxidase activity in vivo.Agents Actions. 1981 Apr;11(1-2):20-7. doi: 10.1007/BF01991449. Agents Actions. 1981. PMID: 6787849 Review.
Cited by
-
Histamine Metabolism in IBD: Towards Precision Nutrition.Nutrients. 2025 Jul 29;17(15):2473. doi: 10.3390/nu17152473. Nutrients. 2025. PMID: 40806058 Free PMC article. Review.
References
-
- Cortese S., Song M., Farhat L.C., Yon D.K., Lee S.W., Kim M.S., Park S., Oh J.W., Lee S., Cheon K.-A., et al. Incidence, prevalence, and global burden of ADHD from 1990 to 2019 across 204 countries: Data, with critical re-analysis, from the Global Burden of Disease study. Mol. Psychiatry. 2023;28:4823–4830. doi: 10.1038/s41380-023-02228-3. - DOI - PubMed
-
- Blasco-Fontecilla H., Bella-Fernández M., Wang P., Martin-Moratinos M., Li C. Prevalence and Clinical Picture of Diamine Oxidase Gene Variants in Children and Adolescents with Attention Deficit Hyperactivity Disorder: A Pilot Study. J. Clin. Med. 2024;13:1659. doi: 10.3390/jcm13061659. - DOI - PMC - PubMed
-
- Yue J., Tan Y., Huan R., Guo J., Yang S., Deng M., Xiong Y., Han G., Liu L., Liu J., et al. Mast cell activation mediates blood–brain barrier impairment and cognitive dysfunction in septic mice in a histamine-dependent pathway. Front. Immunol. 2023;14:1090288. doi: 10.3389/fimmu.2023.1090288. - DOI - PMC - PubMed
Publication types
LinkOut - more resources
Full Text Sources