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Review
. 2024 Nov 14;13(22):6857.
doi: 10.3390/jcm13226857.

Myval Transcatheter Heart Valve: The Future of Transcatheter Valve Replacement and Significance in Current Timeline

Teoman Kilic  1 , Senol Coskun  2 , Didar Mirzamidinov  1 , Irem Yilmaz  1 , Sadan Yavuz  3 , Tayfun Sahin  1
Affiliations
Review

Myval Transcatheter Heart Valve: The Future of Transcatheter Valve Replacement and Significance in Current Timeline

Teoman Kilic et al. J Clin Med. .

Abstract

The Myval is a balloon-expandable transcatheter heart valve (THV) developed by Meril Life Sciences Pvt. Ltd. (Vapi, Gujarat, India) that has an innovative operator-friendly design that aids in improving deliverability and features precise deployment. Various clinical studies demonstrate its effectiveness and safety, making it a promising choice in valvular interventions. Myval has been successfully utilized as a transcatheter aortic valve implantation (TAVI) device in cases with conduction disturbances, bicuspid aortic valve anatomy, non-calcified aortic regurgitation, dysfunctional stenosed right ventricular outflow tract (RVOT) conduits, pulmonary valve replacement, mitral valve replacement, and valve-in-valve and valve-in-ring implantation procedures. Myval's diverse sizes are also of key importance in complex cases of large annuli and complex anatomy. Further long-term studies are needed to consolidate these results. Its introduction signifies a significant advancement in cardiology, aiming to enhance patient outcomes and quality of life. In the present review, we provide an update on new-generation Myval THV series and review the available clinical data published to date with an emphasis on diverse use in specific clinical scenarios.

Keywords: Myval; safety; transcatheter aortic valve implantation; transcatheter heart valve; valve-in-valve implantation.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Structural overview and salient features of the Myval transcatheter heart valve.
Figure 2
Figure 2
Design and key features of the new-generation Myval Octacor THV system.
Figure 3
Figure 3
Diverse use of new-generation Myval THV system in different clinical scenarios.
See this image and copyright information in PMC

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