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Review
. 2024 Nov 8;13(11):977.
doi: 10.3390/pathogens13110977.

How to Manage a Neonate Born from a SARS-CoV-2-Positive Mother: A Narrative Review

Serena Salomè  1 , Ida D'Acunzo  1 , Federica Fanelli  1 , Simona Perniciaro  2 , Letizia Capasso  1 , Francesco Raimondi  1 , Chryssoula Tzialla  3 , On Behalf Of The Study Group Of Neonatal Infectious Diseases
Affiliations
Review

How to Manage a Neonate Born from a SARS-CoV-2-Positive Mother: A Narrative Review

Serena Salomè et al. Pathogens. .

Abstract

From 2020 to today, considerable knowledge on SARS-CoV-2 has been collected, even on pregnant women and their fetuses and newborns, and clinical guidelines have been written and implemented worldwide. Vaccination has considerably improved outcomes, but hesitancy amongst pregnant patients and the emergence of variants remain challenging, and SARS-CoV-2 positivity during pregnancy continues to be associated with an increased risk of maternal complications, premature delivery, and higher neonatal mortality and morbidity. A body of data now exists on the effect of SARS-CoV-2 during pregnancy on early neonatal outcomes, medical education in obstetrics and pediatrics, and longer-term developmental outcomes. This review aimed to present important findings on clinical outcomes and health recommendations for neonate born from a SARS-CoV-2-positive mother in order to summarize effective preventive healthcare guidelines.

Keywords: COVID-19; MIS-N; SARS-CoV2; neonatal outcome.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Multisystemic manifestation of MIS-N (modified from Mascarenhas et al. [63]).
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