Extracorporeal Organ Support for Burn-Injured Patients
- PMID: 39599979
- PMCID: PMC11540296
- DOI: 10.3390/ebj5020006
Extracorporeal Organ Support for Burn-Injured Patients
Abstract
As mortality relating to severe acute burn injury improves, patients are surviving longer into the critical care phase, which is commonly complicated by multisystem organ failure. Extracorporeal organ support (ECOS) represents a set of potential therapeutic technologies for managing patients with organ-specific complications. This article provides a comprehensive review of the existing literature, focusing on the use of continuous kidney replacement therapy, extracorporeal membrane oxygenation, extracorporeal carbon dioxide removal, and extracorporeal blood purification. Though promising, many of these technologies are in the early phases of implementation and are restricted to well-resourced medical systems, limiting their use in large scale casualty and austere scenarios.
Keywords: burn; carbon dioxide; extracorporeal; kidney; oxygenation; purification.
Conflict of interest statement
The authors declare no conflicts of interest. The views expressed herein are those of the authors and do not reflect the official policy or position of the Department of the Army, the Department of the Air Force, the Department of Defense, or the U.S. Government.
References
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- American Burn Association . Annual Burn Injury Summary Report 2022 Update. Oxford University Press; Oxford, UK: 2023.
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- Culnan D.M., Sherman W.C., Chung K.K., Wolf S.E. Critical care in the severely burned: Organ support and management of complications. In: Herndon D.N., editor. Total Burn Care. 8th ed. Elsevier; Amsterdam, The Netherlands: 2018. pp. 328–354.
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