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. 1986 Apr;320(6062):501-6.
doi: 10.1038/320501a0.

DNA bending at adenine . thymine tracts

H S Koo, H M Wu, D M Crothers

DNA bending at adenine . thymine tracts

H S Koo et al. Nature. 1986 Apr.

Abstract

Intrinsic bending of DNA molecules results from local structural polymorphism in regions of homopolymeric dA . dT which are at least 4 base pairs long; the A . T tracts must be repeated in phase with the helix screw. Bending, in the direction of base-pair tilt rather than roll, occurs at the junctions between the A . T tract and adjacent B-DNA, with a larger angle at the 3' than at the 5' end of the A tract.

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