ENGases to treat IgG-mediated diseases

Comment

Sarah Crunkhorn. Nat Rev Drug Discov. 2025 Jan.

. 2025 Jan;24(1):17.

doi: 10.1038/d41573-024-00190-5.

No abstract available

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Potent efficacy of an IgG-specific endoglycosidase against IgG-mediated pathologies.
Sastre DE, Bournazos S, Du J, Boder EJ, Edgar JE, Azzam T, Sultana N, Huliciak M, Flowers M, Yoza L, Xu T, Chernova TA, Ravetch JV, Sundberg EJ. Sastre DE, et al. Cell. 2024 Nov 27;187(24):6994-7007.e12. doi: 10.1016/j.cell.2024.09.038. Epub 2024 Oct 21. Cell. 2024. PMID: 39437779 Free PMC article.

1. Sastre, D. E. et al. Potent efficacy of an IgG-specific endoglycosidase against IgG-mediated pathologies. Cell https://doi.org/10.1016/j.cell.2024.09.038 (2024)