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. 2024 Nov 13:11:1510463.
doi: 10.3389/fmed.2024.1510463. eCollection 2024.

Emerging trends and hotspots in intestinal microbiota research in sepsis: bibliometric analysis

Zhengyi Zhang  1 , Meijie Yang  1 , Tong Zhou  1 , Yingjie Chen  2 , Xiujuan Zhou  2 , Kunlan Long  2
Affiliations

Emerging trends and hotspots in intestinal microbiota research in sepsis: bibliometric analysis

Zhengyi Zhang et al. Front Med (Lausanne). .

Abstract

Background: The association between the gut microbiota and sepsis has garnered attention in the field of intestinal research in sepsis. This study utilizes bibliometric methods to visualize and analyze the literature on gut microbiota research in sepsis from 2011 to 2024, providing a scientific foundation for research directions and key issues in this domain.

Methods: Original articles and reviews of gut microbiota research in sepsis, which published in English between 2011 and 2024, were obtained from the Web of Science Core Collection on June 21, 2024. Python, VOSviewer, and CiteSpace software were used for the visual analysis of the retrieved data.

Results: A total of 1,031 articles were analyzed, originating from 72 countries or regions, 1,614 research institutions, and 6,541 authors. The articles were published in 434 different journals, covering 89 different research fields. The number of publications and citations in this research area showed a significant growth trend from 2011 to 2024, with China, the United States, and the United Kingdom being the main research forces. Asada Leelahavanichkul from Thailand was identified as the most prolific author, making him the most authoritative expert in this field. "Nutrients" had the highest number of publications, while "Frontiers in Cellular and Infection Microbiology," "Frontiers in Immunology" and "the International Journal of Molecular Sciences" have shown increasing attention to this field in the past 2 years. Author keywords appearing more than 100 times included "gut microbiota (GM)," "sepsis" and "microbiota." Finally, this study identified "lipopolysaccharides (LPS)," "short-chain fatty acids (SCFAs)," "probiotics," "fecal microbiota transplantation (FMT)" and "gut-liver axis" as the research hotspots and potential frontier directions in this field.

Conclusion: This bibliometric study summarizes current important perspectives and offers comprehensive guidance between sepsis and intestinal microbiota, which may help researchers choose the most appropriate research directions.

Keywords: CiteSpace; VOSviewer; bibliometric; intestinal microbiota; sepsis.

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Conflict of interest statement

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Figures

Figure 1
Figure 1
Flowchart of literature search selection.
Figure 2
Figure 2
Trends in the growth of publications and the number of citations in sepsis and intestinal microbiota.
Figure 3
Figure 3
Cooperation map of authors in sepsis and intestinal microbiota.
Figure 4
Figure 4
Cooperation map of institutions in sepsis and intestinal microbiota.
Figure 5
Figure 5
Cooperation map of countries regions in sepsis and intestinal microbiota.
Figure 6
Figure 6
Bubble chart of the top 20 journals by year.
Figure 7
Figure 7
Bubble chart of the top 20 research areas by year.
Figure 8
Figure 8
Cooperation map of author keywords in sepsis and intestinal microbiota.
Figure 9
Figure 9
Bubble chart of the top 30 author keywords by year.
Figure 10
Figure 10
The clustered network map of Keywords in sepsis and intestinal microbiota.
Figure 11
Figure 11
The clustered network map of reference in sepsis and intestinal microbiota.
Figure 12
Figure 12
Top 25 References with the Strongest Citation Bursts.
See this image and copyright information in PMC

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