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Review
. 2025 Jan;15(1):15-29.
doi: 10.1007/s13555-024-01311-z. Epub 2024 Nov 28.

Frontal Fibrosing Alopecia: A Comprehensive Guide for Cosmetic Dermatologists

Affiliations
Review

Frontal Fibrosing Alopecia: A Comprehensive Guide for Cosmetic Dermatologists

Marina Landau et al. Dermatol Ther (Heidelb). 2025 Jan.

Abstract

Frontal fibrosing alopecia (FFA) is an inflammatory, scarring hair loss that commonly affects postmenopausal women and presents as frontal hairline recession, facial papules, loss of eyebrows, and facial hyperpigmentation. Because of the chronic, progressive nature of this disease and its important impact on aesthetic appearance, patients often consult dermatologists to improve unwanted FFA symptoms. Cosmetic practices including the use of non-ablative lasers, autologous fat injections, and oral isotretinoin can improve FFA-associated facial vein prominence, atrophic indentations, and facial papules, respectively. On the other hand, while exact etiology underlying FFA development remains unclear, some procedures including deep chemical peels and ablative laser therapies have been shown to induce facial scarring and are contraindicated in patients with FFA. In the same way, some cosmetic ingredients can possibly be a triggering or worsening factor for FFA as well. Therefore, it is essential for dermatologists to be aware of both the benefits and risks of cosmetic treatments in patients with diagnosed or suspected FFA. This comprehensive review aims to outline the key cosmetic products and procedures that may be useful in patients with FFA and those which should be considered contraindicated.

Keywords: Botulinum toxin; Chemical peel; Contraindicated procedures; Facial scarring; Filler injection; Laser; Microneedling; Personal-care products; Sunscreens.

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Conflict of interest statement

Declarations. Conflict of Interest: Antonella Tosti is a consultant for DS Laboratories, Almirall, Thirty Madison, Eli Lilly, Bristol Myers Squibb, P&G, Pfizer, SUNpharma, and Myovant. Antonella Tosti is an Editorial Board member of Dermatology and Therapy, Antonella Tosti was not involved in the selection of peer reviewers for the manuscript nor any of the subsequent editorial decisions. Marina Landau and Sofia M. Perez have no conflicts to declare. Ethical Approval: This article is based on previously conducted studies and does not contain any new studies with human participants or animals performed by any of the authors.

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