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. 2025 May 12;31(5):1471-1472.
doi: 10.1093/ibd/izae284.

Potential Utility of Laser Speckle Contrast Imaging to Detect Early Microcirculatory Changes Associated With Erythema Nodosum in Crohn's Disease: A Case Report

EunMee Yang  1 , Peter M Wayne  1 , Andrew C Ahn  1 , Joshua Korzenik  2
Affiliations

Potential Utility of Laser Speckle Contrast Imaging to Detect Early Microcirculatory Changes Associated With Erythema Nodosum in Crohn's Disease: A Case Report

EunMee Yang et al. Inflamm Bowel Dis. .
No abstract available

Keywords: Crohn’s disease; cutaneous blood perfusion; erythema nodosum; inflammatory bowel disease; laser speckle contrast imaging.

Plain language summary

In this case report of a young female patient with Crohn’s disease, presenting with erythema nodosum, laser speckle contrast imaging was able to detect blood flow changes in the affected skin area before clinical signs of the skin lesion emerged.

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Conflict of interest statement

None declared.

Figures

Figure 1.
Figure 1.
Cutaneous blood perfusion of the right lower extremity at 2 time points, showing progression of erythema nodosum (EN) in a patient with Crohn’s disease. A and B, Photographs of the anterior aspect and distal portion of the patient’s right lower extremity. Dotted white oval in panel B indicates the skin area affected by EN. C and D, Perfusion images corresponding to the anterior, anterolateral, and anteromedial aspects of the patient’s right lower extremity were obtained with laser speckle contrast imaging. Dotted white circle in panel C shows a focal point on the anteromedial aspect of the patient’s right lower extremity exhibiting higher blood perfusion.
See this image and copyright information in PMC

References

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