Disclosures Dr M.L. Shiffman has received fees for participating in advisor meetings with CymaBay, Exelixis, HepQuant, Intercept, Ipsen, and Mirum; consulting fees from Intra-Sana; grant support from Akero, Altimmune, 89Bio, Camurus, CymaBay, Durect, Galectin, Genentech, Gilead, HepQuant, Hamni, HighTide, Intercept, Inventiva, Ipsen, Madrigal, Mirum, Novo Nordisk, Oncoustics, Pliant, Salix, Viking, and Zydus; and speakers fees from Genentech, Gilead, Intercept, Intra-Sana, Ipsen, and Mallinckrodt.