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Case Reports
. 2024 Oct-Dec;31(4):351-354.
doi: 10.4103/jfcm.jfcm_143_24. Epub 2024 Oct 10.

Immunoglobulin G4-related pancreatitis presenting as an obstructive pancreatic mass in a Latino male

Blake Busey  1 , Paul Estrada  2 , Javaria Anwer  3
Affiliations
Case Reports

Immunoglobulin G4-related pancreatitis presenting as an obstructive pancreatic mass in a Latino male

Blake Busey et al. J Family Community Med. 2024 Oct-Dec.

Abstract

Immunoglobulin G4-related disease (IgG4-RD) is a localized or diffuse autoimmune fibro-inflammatory condition that can affect any organ. The literature is sparse on IgG4-RD in the Latino population. This is a case report of a Latino male diagnosed with IgG4-related pancreatitis presenting as a mass. Our 40-year-old Latino male patient presented with diarrhea and epigastric discomfort progressing to jaundice and pruritus. He had associated elevations in liver enzymes, antinuclear antibody, and IgG4. Magnetic resonance cholangiopancreatography revealed a lobulated pancreatic head mass with common bile duct (CBD) narrowing. Endoscopic ultrasound-guided biopsy of the pancreas revealed no malignancy, and the patient underwent CBD stenting through endoscopic retrograde cholangiopancreatography. The patient demonstrated a favorable response to systemic glucocorticoid therapy with resolution of his symptoms and normalization of his liver function tests. Coronavirus disease-2019 infection during treatment had no impact on the outcomes.

Keywords: Endoscopic retrograde cholangiopancreatography; Latino; immunoglobulin G4; pancreatic mass; pancreatitis.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Endoscopic retrograde cholangiopancreatography and endoscopic ultrasound with biopsy of pancreatic mass as well as stenting of the common bile duct. Biliary dilation noted in the mid to upper common bile duct with tapering and stenosis at the lower portion of the duct
Figure 2
Figure 2
Repeat endoscopic retrograde cholangiopancreatography and endoscopic ultrasound with no residual mass identified, common bile duct stent removed. Duct no longer dilated and stenosis have resolved
See this image and copyright information in PMC

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