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Case Reports
. 2024 Dec 4;17(12):e262695.
doi: 10.1136/bcr-2024-262695.

Impact of somato-cognitive coordination therapy on activities of daily living in a patient with Huntington's disease

Keito Shinmoto  1   2 , Yuki Torikai  3 , Masahiko Hara  3   4
Affiliations
Case Reports

Impact of somato-cognitive coordination therapy on activities of daily living in a patient with Huntington's disease

Keito Shinmoto et al. BMJ Case Rep. .

Abstract

Huntington's disease (HD) causes progressive neurodegeneration, impairing activities of daily living (ADL). Treatment focuses primarily on symptomatic relief through multidisciplinary approaches. This case report examines the impact of somato-cognitive coordination therapy (SCCT) on ADL in a patient with HD. A woman in her 40s with early-stage HD underwent 22 SCCT sessions using the mediVR KAGURA (mediVR), a virtual reality technology-based medical device over 20 months. Her total functional capacity rating scale improved from 10 to 11 and her Barthel Index improved from 90 to 100 within 3 months, allowing her to continue working. These improvements were sustained for 17 months. Objective measures like the single-leg stance test showed consistent progress. Improved cognitive function and psychiatric well-being were also suggested by the Trail Making Test and a return to hobbies like hiking. SCCT may have the potential to improve ADL and could complement multidisciplinary care strategy for HD patients.

Keywords: Cognitive behavioural psychotherapy; Movement disorders (other than Parkinsons); Neuro genetics; Parkinson's disease.

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Conflict of interest statement

Competing interests: mediVR KAGURA is a medical device of mediVR, Inc. MH is a director and holds private equity in mediVR, Inc. KS and YT are full-time employees of mediVR, Inc. mediVR, Inc. runs the mediVR Rehabilitation Center. MH is a director and holds private equity in mediVR, Inc. KS and YT are full-time employees of mediVR, Inc. The lead clinician has ensured the veracity of all author declarations of conflict of interest and author disclosures.

Figures

Figure 1
Figure 1. mediVR KAGURA-Guided Somato-Cognitive Coordination Therapy in Huntington’s disease.
Figure 2
Figure 2. Subjective and objective measures over 20 months of Huntington’s disease treatment.
See this image and copyright information in PMC

References

    1. McColgan P, Tabrizi SJ. Huntington’s disease: a clinical review. Eur J Neurol. 2018;25:24–34. doi: 10.1111/ene.13543. - DOI - PubMed
    1. Stoker TB, Mason SL, Greenland JC, et al. Huntington’s disease: diagnosis and management. Pract Neurol. 2022;22:32–41. doi: 10.1136/practneurol-2021-002937. - DOI - PubMed
    1. Tabrizi SJ, Estevez-Fraga C, Roon-Mom WMC, et al. Potential disease-modifying therapies for Huntington’s disease: lessons learned and future opportunities. Lancet Neurol. 2022;21:645–58. doi: 10.1016/S1474-4422(22)00141-7. - DOI - PMC - PubMed
    1. Hara M, Murakawa Y, Wagatsuma T, et al. Feasibility of somato-cognitive coordination therapy using virtual reality for patients with advanced severe Parkinson’s disease. J Parkinsons Dis. 2024;14:895–8. doi: 10.3233/JPD-223423. - DOI - PMC - PubMed
    1. Takimoto K, Omon K, Murakawa Y, et al. Case of cerebellar ataxia successfully treated by virtual reality-guided rehabilitation. BMJ Case Rep. 2021;14:e242287. doi: 10.1136/bcr-2021-242287. - DOI - PMC - PubMed

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