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. 1986 May;143(5):650-1.
doi: 10.1176/ajp.143.5.650.

Does carbamazepine-induced reduction of plasma haloperidol levels worsen psychotic symptoms?

G W Arana, D C Goff, H Friedman, M Ornsteen, D J Greenblatt, B Black, R I Shader

Does carbamazepine-induced reduction of plasma haloperidol levels worsen psychotic symptoms?

G W Arana et al. Am J Psychiatry. 1986 May.

Abstract

Seven psychotic patients' plasma haloperidol levels, determined with gas-liquid chromatography, fell a mean of 60% when carbamazepine treatment was instituted. Two patients' levels became undetectable, and their symptoms worsened. Haloperidol level monitoring may be required for patients given both haloperidol and carbamazepine.

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