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Meta-Analysis
. 2024 Dec;47(12):e70053.
doi: 10.1002/clc.70053.

Effect of Postoperative Atrial Fibrillation After Cardiac Surgery: A Meta-Analysis

Fangzhou Qu  1 , Wei Yang  2 , Ni He  3 , Shangcheng Qu  4 , Xiao Zhou  5 , Huayan Ma  1 , Xin Jiang  3
Affiliations
Meta-Analysis

Effect of Postoperative Atrial Fibrillation After Cardiac Surgery: A Meta-Analysis

Fangzhou Qu et al. Clin Cardiol. 2024 Dec.

Abstract

Background: A meta-analysis study was conducted to determine how to predict the effect of postoperative atrial fibrillation after cardiac surgery.

Hypothesis: Long-term mortality and cardiovascular morbidity are linked to postoperative atrial fibrillation.

Method: Until August 2024, a comprehensive literature study was completed, and 3486 connected studies were revised. The 38 selected studies included 241 299 cardiac surgery participants at the beginning of the study. The odds ratio (OR) and 95% confidence intervals (CIs) were used to look at the effect of atrial fibrillation after heart surgery using two-sided methods and either a fixed or random model.

Results: Individuals with cardiac surgery with postoperative atrial fibrillation had significantly higher mortality at 1 year (OR, 1.39; 95% CI, 1.12-1.72, p < 0.001), mortality at 5 years (OR, 1.61; 95% CI, 1.33-1.94, p < 0.001), mortality at 10 years (OR, 1.61; 95% CI, 1.39-1.87, p < 0.001), and overall stroke (OR, 1.61; 95% CI, 1.34-1.94, p < 0.001) compared to without postoperative atrial fibrillation.

Conclusions: Individuals with cardiac surgery with postoperative atrial fibrillation had significantly higher mortality at 1 year, mortality at 5 years, mortality at 10 years, and overall stroke compared to those without postoperative atrial fibrillation. To validate this discovery, more research and caution must be implemented when interacting with its values.

Keywords: cardiac surgery; mortality at 1 year; mortality at 10 year; mortality at 5 year; overall stroke; postoperative atrial fibrillation.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
A procedure flowchart for the research.
Figure 2
Figure 2
Forest plot of comparison of influence on mortality after 1 year of cardiac surgery of postoperative atrial fibrillation and no postoperative atrial fibrillation.
Figure 3
Figure 3
Forest plot of comparison of influence on mortality after 5 years of cardiac surgery of postoperative atrial fibrillation and no postoperative atrial fibrillation.
Figure 4
Figure 4
Forest plot of comparison of influence on mortality after 10 years of cardiac surgery of postoperative atrial fibrillation and no postoperative atrial fibrillation.
Figure 5
Figure 5
The with postoperative atrial fibrillation compared to without postoperative atrial fibrillation forest plot influence on overall stroke in cardiac surgery.
See this image and copyright information in PMC

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References

    1. Filardo G., Damiano R. J., Ailawadi G., et al., “Epidemiology of New‐Onset Atrial Fibrillation Following Coronary Artery Bypass Graft Surgery,” Heart 104, no. 12 (2018): 985–992. - PubMed
    1. Lowres N., Mulcahy G., Jin K., Gallagher R., Neubeck L., and Freedman B., “Incidence of Postoperative Atrial Fibrillation Recurrence in Patients Discharged in Sinus Rhythm After Cardiac Surgery: A Systematic Review and Meta‐Analysis†,” Interactive Cardiovascular and Thoracic Surgery 26, no. 3 (2017): 504–511. - PubMed
    1. Kirchhof P., Benussi S., Kotecha D., et al., “2016 ESC Guidelines for the Management of Atrial Fibrillation Developed in Collaboration With EACTS,” European Journal of Cardio‐Thoracic Surgery 50, no. 5 (2016): e1–e88. - PubMed
    1. Kaw R., Hernandez A. V., Masood I., Gillinov A. M., Saliba W., and Blackstone E. H., “Short‐ and Long‐Term Mortality Associated With New‐Onset Atrial Fibrillation After Coronary Artery Bypass Grafting: A Systematic Review and Meta‐Analysis,” Journal of Thoracic and Cardiovascular Surgery 141, no. 5 (2011): 1305–1312. - PubMed
    1. Stroup D. F., “Meta‐Analysis of Observational Studies in Epidemiology: A Proposal for Reporting,” Journal of the American Medical Association 283, no. 15 (2000): 2008–2012. - PubMed

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