Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Dec 4;82(1):233.
doi: 10.1186/s13690-024-01462-7.

Temporal trends of incidence, mortality, and survival of liver cancer during 2011-2020 in Fujian Province, Southeast China

Zhisheng Xiang #  1 , Yongying Huang #  1 , Jingyu Ma  1 , Yongtian Lin  1 , Yeying Wen  1 , Yan Zhou  2 , Jingfeng Liu  3   4
Affiliations

Temporal trends of incidence, mortality, and survival of liver cancer during 2011-2020 in Fujian Province, Southeast China

Zhisheng Xiang et al. Arch Public Health. .

Abstract

Background: Liver cancer is a common malignant tumor of the digestive system. We aimed to estimate the trend in the burden of liver cancer in Fujian Province, China, during 2011-2020.

Methods: The population-based cancer data was collected from the cancer registry in Fujian Province during 2011-2020. Segi's world standard population was used to calculate the age-standardized incidence rates and age-standardized mortality rates. The temporal trend of liver cancer was displayed by annual percentage change and average annual percentage change (AAPC). Relative survival of liver cancer was calculated as the ratio of observed survival to expected survival. The age-standardized relative survival was calculated according to the International Cancer Survival Standards 1.

Results: There were 14,725 patients diagnosed with liver cancer and 12,698 patients died between 2011 and 2020. For males, there was a downward trend in incidence and mortality (AAPC: -3.86%, -3.44%). Similarly, the downward trend was also shown in females (AAPC: -3.96%, -2.79%). The highest age-specific incidence and mortality were in the 75-79 age group (146.59/100,000 and 137.99/100,000, respectively), and there was no downward trend in this group during the period. The overall age-standardized 5-year relative survival was 10.77% in 2011-2015 and 14.54% in 2016-2020. During the study period, the percentage improvement of survival was higher in males than in females (34.75% and 25.33%). The percentage improvement of survival in urban was higher than that in rural (38.64% and 28.75%). Except for the age group over 75, the survival of patients in other age groups all has improved.

Conclusions: Liver cancer remains a serious public health problem in Fujian Province, China, which needs to be solved, especially in some high-risk groups such as the elderly, high-risk males, and rural populations. Early detection and treatment is the key to the prevention and treatment of liver cancer.

Keywords: Incidence; Live cancer; Mortality; Survival; Trend.

PubMed Disclaimer

Conflict of interest statement

Declarations. Ethics approval and consent to participate: The Ethics Committee of Fujian Cancer Hospital determined that ethics approval and informed consent were not required for this research, because this was a retrospective study that used source data that were completely unidentifiable, and all data were anonymous. Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
The temporal trend of age-standardized incidence and mortality of liver cancer in males and females between 2011 and 2020 in Fujian Province, China
Fig. 2
Fig. 2
The age-specific incidence (A) and mortality (B) of liver cancer in males and females during 2011–2020 in Fujian Province, China
Fig. 3
Fig. 3
The survival curve of liver cancer in Fujian Province, China, 2011–2015 and 2016–2020
Fig. 4
Fig. 4
The 5-year relative survival of liver cancer in gender (A), region (B), and age group (C) in Fujian Province, China. A p-value of less than 0.05 was considered statistically significant in the differences in survival across various periods, categorized by gender, region, and age. RS, relative survival
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Devarbhavi H, Asrani SK, Arab JP, Nartey YA, Pose E, Kamath PS. Global burden of liver disease: 2023 update. J Hepatol. 2023;79(2):516–37. 10.1016/j.jhep.2023.03.017. - PubMed
    1. Bray F, Laversanne M, Sung H, Ferlay J, Siegel R, Soerjomataram I, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74(3):229–63. 10.3322/caac.21834. - PubMed
    1. Wang D, Hu X, Xu H, Chen Y, Wang S, Lin G, et al. Trend analysis and age-period-cohort effects on morbidity and mortality of liver cancer from 2010 to 2020 in Guangzhou, China. Front Oncol. 2014;14:1387587. 10.3389/fonc.2024.1387587. - PMC - PubMed
    1. Bai L, Liu Z, Fang Q, Yan Q, Shi O, Bao P, et al. The trends and projections in the incidence and mortality of liver cancer in urban Shanghai: a population-based study from 1973 to 2020. Clin Epidemiol. 2018;10:277–88. 10.2147/CLEP.S153951. - PMC - PubMed
    1. Han B, Zheng R, Zeng H, Wang S, Sun K, Chen R, et al. Cancer incidence and mortality in China, 2022. J Natl Cancer Cent. 2024;4(1):47–53. 10.1016/j.jncc.2024.01.006. - PMC - PubMed

LinkOut - more resources