Uncommon primary nasosinusal B-cell lymphoma in children: A case report

Abstract

This review presents the case of a 9-year-old patient who reported headaches and unilateral nasal obstruction, without fever, and with a generally preserved condition. An endoscopic examination revealed a polypoid fleshy mass in the left nasal cavity, along with purulent secretions reaching the inferior turbinate. These findings prompted a facial CT scan to assess the nature of the lesion and the extent of infiltration into surrounding structures. A biopsy and histological analysis confirmed the diagnosis of B-cell lymphoma in the nasal sinuses, a rare occurrence in children. The unusual presentation of this case makes it worthy of sharing.

Keywords: Lymphoma B; Nasopharyngeal.

Fig. 1

The axial section of a facial CT scan reveals a heterogeneous tissue lesion centered on the left maxillary sinus.

Fig. 2

The coronal section of the facial CT scan shows a heterogeneous tissue lesion centered on the left maxillary sinus with lysis of the medial wall and invasion of the lower nasal turbinate.

Fig. 3

The facial CT sagittal section shows a heterogeneous tissue lesion centered on the left maxillary sinus with lysis of the upper wall and invasion of extraconal fat.

Fig. 4

The tumor proliferation in diffuse architecture is composed of large, isolated cells with rounded nuclei and precise limits; the cytoplasm is abundantly eosinophilic and contains some mitotic figures (arrows).

Fig. 5

The process involves the diffuse labeling of tumor cells with PAX5 and CD20 receptors.