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. 2024 Dec 1;9(4):267-280.
doi: 10.22540/JFSF-09-267. eCollection 2024 Dec.

Post-Physical Therapy 4-Month In-Home Dynamic Standing Protocol Maintains Physical Therapy Gains and Improves Mobility, Balance Confidence, Fear of Falling and Quality of Life in Parkinson's Disease: A Randomized Controlled Examiner-Blinded Feasibility Clinical Trial

Miriam van Emde Boas  1   2   3 , Chatkaew Pongmala  1   2   3 , Abigail M Biddix  1   2   3 , Alexis Griggs  1   2   3 , Austin T Luker  1   2   3 , Giulia Carli  1   2   4 , Uros Marusic  5   6 , Nicolaas I Bohnen  1   2   3   7
Affiliations

Post-Physical Therapy 4-Month In-Home Dynamic Standing Protocol Maintains Physical Therapy Gains and Improves Mobility, Balance Confidence, Fear of Falling and Quality of Life in Parkinson's Disease: A Randomized Controlled Examiner-Blinded Feasibility Clinical Trial

Miriam van Emde Boas et al. J Frailty Sarcopenia Falls. .

Abstract

Objective: Parkinson's patients will experience mobility disturbances with disease progression. Beneficial effects of physical therapy are short-lasting. Novel interventions are needed to maintain these benefits.

Methods: Fourteen Parkinson's patients (71±4.08 years) participated in a randomized controlled examiner-blinded feasibility clinical trial. After 12 physical therapy sessions, the intervention group received a height-adjustable desk that facilitates stepping while standing, for 4 months. Explorative outcome measures included MDS-UPDRS II, III, TUG, 8.5m walking test, PDQ-39, sABC, sFES, DEXA scans, and lower extremity strength.

Results: Post-physical-therapy, everyone significantly improved on the MDS-UPDRS II, III, TUG, and 8.5m walking test, and PDQ-39. (p<0.05) After 4 months, the control group regressed towards pre-physical-therapy values. In the intervention group, sedentary behavior decreased beyond desk use, indicating a carry-over effect. MDS-UPDRS II, PDQ-39, sFES, sABC, TUG, 8.5m walking test, activity time, sitting time, hip strength all improved with clinically relevant effect sizes.

Conclusion: Post-physical therapy in-home reduction of sedentary behavior was associated with maintenance of physical benefits and additional improvements in mobility, activity time, balance and quality of life.

Keywords: Parkinson’s Disease; Physical Therapy; Quality of Life; Sarcopenia; Sedentarism.

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Figures

Figure 1
Figure 1
Image of the Height adjustable instrumental Activities of daily living Moving Desk.
Figure 2
Figure 2
Flowchart of the study.
Figure 3
Figure 3
HiAMD utilization during 16-wk intervention.
Figure 4
Figure 4
Visual concept of HiAMD use.
See this image and copyright information in PMC

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