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Review
. 2025 Jan;41(1):19-21.
doi: 10.1016/j.pt.2024.11.010. Epub 2024 Dec 5.

Entering the spatial age of parasite genomics

Sarah K Buddenborg  1 , Stephen R Doyle  2
Affiliations
Free article
Review

Entering the spatial age of parasite genomics

Sarah K Buddenborg et al. Trends Parasitol. 2025 Jan.
Free article

Abstract

Reconciling organism-scale biology at cellular-scale resolution has been a monumental challenge. Recently, Gramberg et al. uncovered the spatial organisation of gene expression in the common liver fluke, Fasciola hepatica. These data provide new insights and opportunities for understanding the fundamental developmental and functional biology of parasites and new targets for control.

Keywords: Fasciola hepatica; drug resistance; drug targets; genomics; helminths; spatial transcriptomics.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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