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. 1986 Mar;61(3):274-7.
doi: 10.1136/adc.61.3.274.

Histological abnormalities in biopsies from macroscopically normal colonoscopies

I R Sanderson, S Boyle, C B Williams, J A Walker-Smith

Histological abnormalities in biopsies from macroscopically normal colonoscopies

I R Sanderson et al. Arch Dis Child. 1986 Mar.

Abstract

One hundred and nineteen children with gastrointestinal symptoms underwent colonoscopy during the course of one year. Out of 39 children that were reported as yielding normal results on endoscopic examination, six had disease detectable only by histology. The pathology included cases of microscopic colitis, Crohn's disease, and indeterminate colitis. To exclude large bowel inflammation as a cause of gastrointestinal symptoms biopsy specimens should always be taken at endoscopy.

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