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Comment
. 2024 Dec 5;84(23):4473-4475.
doi: 10.1016/j.molcel.2024.11.005.

Silent silencers: Leave no trace

Dogancan Ozturan  1 , Carl G de Boer  2
Affiliations
Comment

Silent silencers: Leave no trace

Dogancan Ozturan et al. Mol Cell. .

Abstract

The regulatory mechanisms of silencers have remained poorly understood. In this issue, Hofbauer et al.1 conduct a genome-wide screen in Drosophila melanogaster and reveal three silencer types that appear to work alone-without the need for combinatorial action, traditional chromatin marks, or open chromatin regions.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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