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. 2024 Dec 5;31(12):1719-1721.
doi: 10.1016/j.stem.2024.11.004.

Brain reboot: Enhancing neurogenesis and resilience

David F Butler  1 , Andrew S Yoo  2
Affiliations

Brain reboot: Enhancing neurogenesis and resilience

David F Butler et al. Cell Stem Cell. .

Abstract

In this issue of Cell Stem Cell, Shen et al. investigate in vivo transient expression of Yamanaka factors (YFs) during embryogenesis and an adult mouse model of Alzheimer's disease (AD)-associated amyloidosis. These studies demonstrate that transient induction of YFs may be capable of enhancing neurogenesis and offer resilience against neurodegeneration.

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Conflict of interest statement

Declaration of interests The authors declare no competing interests.

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