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Review
. 2024 Nov 27;17(3):e23.
doi: 10.12786/bn.2024.17.e23. eCollection 2024 Nov.

Stroke-Related Sarcopenia: Pathophysiology and Diagnostic Tools

Jinmann Chon  1 , Yunsoo Soh  1 , Ga Yang Shim  1
Affiliations
Review

Stroke-Related Sarcopenia: Pathophysiology and Diagnostic Tools

Jinmann Chon et al. Brain Neurorehabil. .

Abstract

Sarcopenia is characterized by the progressive loss of muscle mass and strength and can be categorized as either primary or secondary. Patients who have experienced a stroke may develop sarcopenia, which can adversely impact their functional recovery. The pathophysiology of sarcopenia related to stroke involves nutritional deficiency, disuse atrophy, denervation, and metabolic disturbance. Various evaluation tools are available to diagnose this condition, assessing skeletal muscle mass, muscle strength, and physical function. However, due to the limitations of traditional sarcopenia diagnostic criteria in the context of stroke, there is pressing need to establish diagnostic standards that accurately reflect the disabilities experienced by patients with stroke.

Keywords: Diagnosis; Pathophysiology; Sarcopenia; Stroke.

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Conflict of interest statement

Conflict of Interest: The authors have no potential conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1. Algorithm for sarcopenia evaluation based on the Asian Working Group for Sarcopenia 2019 guidelines.
SARC-F, sarcopenia screening questionnaire; M, male; F, female; SARC-CalF, sarcopenia screening questionnaire adding calf circumference; LMM, low muscle mass; LMS, low muscle strength; LPP, low physical performance; DEXA, dual-energy X-ray absorptiometry; BIA, bioimpedance analysis.
See this image and copyright information in PMC

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