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Case Reports
. 1985 Jan 1;55(1):186-9.
doi: 10.1002/1097-0142(19850101)55:1<186::aid-cncr2820550129>3.0.co;2-x.

Medulloblastoma. Period of risk reviewed

J P Latchaw, J F Hahn, D J Moylan, R Humphries, J Mealey Jr
Case Reports

Medulloblastoma. Period of risk reviewed

J P Latchaw et al. Cancer. .

Abstract

Collins postulated that patients with Wilms' tumor surviving for a period equal to their age at diagnosis plus 9 months were no longer at risk for a recurrence. Although this no longer holds for Wilms' tumor, it has been applied to patients with medulloblastoma. Case histories of patients who survived a period of risk designated by Collins' rule and later developed a histologically confirmed recurrent medulloblastoma are discussed. Reported cases violating Collins' rule constitute less than 2% of all medulloblastomas. The continued use of Collins' rule is advocated. Patients who have survived this period of risk, are neurologically stable, and have a negative computerized tomography (CT) head scan are exceedingly unlikely to develop a recurrent medulloblastoma.

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