[Application of Aspergillus-specific immunoglobulin G antibody in the management of pulmonary aspergillosis]

Abstract

Aspergillus causes a range of diseases in patients with immunodeficiency or underlying pulmonary diseases. Aspergillus-specific immunoglobulin G antibody (Asp-IgG) is produced in response to Aspergillus pathopoiesis. Currently, Asp-IgG is included in the diagnostic criteria for chronic pulmonary aspergillosis (CPA) and allergic bronchopulmonary aspergillosis (ABPA). In recent years, some researches have proved that Asp-IgG also has important diagnostic value for non-neutropenic patients with invasive pulmonary aspergillosis (IPA). This review summarized the progress of Asp-IgG in the management of different types of pulmonary aspergillosis, and the advantages of rapid detection methods for Asp-IgG.