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Review
. 2024 Dec 9;20(Suppl 3):64.
doi: 10.1186/s13223-024-00931-6.

Urticaria

Moshe Ben-Shoshan  1 , Amin Kanani  2 , Chrystyna Kalicinsky  3 , Wade Watson  4
Affiliations
Review

Urticaria

Moshe Ben-Shoshan et al. Allergy Asthma Clin Immunol. .

Abstract

Urticaria (hives) is a common disorder that may be associated with angioedema (swelling that occurs beneath the skin). It is generally classified as acute or chronic, and chronic urticaria is further classified as spontaneous or inducible Second-generation, non-sedating histamine type 1 (H1)-receptor antihistamines represent the mainstay of therapy for both acute and chronic urticaria. Second-line treatment for uncontrolled chronic urticaria includes omalizumab (a monoclonal anti-immunoglobulin E [IgE] antibody). In this article, we review the causes, diagnosis and management of urticaria (with or without angioedema).

Keywords: Acute urticaria; Chronic spontaneous urticaria; Chronic urticaria; Inducible urticaria; Urticaria.

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Conflict of interest statement

Declarations. Ethics approval and consent to participate: Not applicable. Consent for publication: Not applicable. Competing interests: Dr. Moshe Ben-Shoshan has received consulting fees from Novartis and Sanofi. Dr. Amin Kanani has received consulting fees and honoraria from Novartis, Medexus Pharmaceuticals, CSL Behring, Aralez Pharmaceuticals, Biocryst and Takeda, and consulting fees, honoraria, and research funding from Novartis, Takeda, Biocryst and Genentech. Dr. Chrystyna Kalicinsky has received honoraria and consulting fees from Takeda, CSL and Biocryst. Dr. Wade Watson is medical advisor for Food Allergy Canada.

Figures

Fig. 1
Fig. 1
Urticaria (hives)
Fig. 2
Fig. 2
Classification of urticaria
Fig. 3
Fig. 3
Simplified stepwise algorithm for the treatment of urticaria [6]. SC: subcutaneously. Adapted from Zuberbier 2022 [6]
See this image and copyright information in PMC

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