Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Dec 9;24(1):1484.
doi: 10.1186/s12903-024-05107-7.

Impact of silica nanoparticles incorporation on the properties of resin infiltration: an in vitro study

Abeer ElSayed ElEmbaby  1 , Adham Essam Nassar  2 , Mohamed Elshirbeny Elawsya  3
Affiliations

Impact of silica nanoparticles incorporation on the properties of resin infiltration: an in vitro study

Abeer ElSayed ElEmbaby et al. BMC Oral Health. .

Abstract

Background: This study evaluated the effect of nano-silica (NS) incorporation with resin infiltrant on water sorption and solubility of resin infiltrant, mineral density of demineralized enamel, and resin tags penetration.

Methods: NS (Sigma-Aldrich, St Louis, Missouri, USA) was added into the resin infiltrant (ICON, DMG, Hamburg, Germany) at two concentrations by weight. The tested groups were: ICON (control), ICON + 0.2, and ICON + 0.5 (n = 10 per group). Water sorption and solubility were assessed using mass variation after 60 days water storage. Mineral density and surface topography were assessed using micro-Computed Tomography scans. Resin tags penetration was measured using a scanning electron microscope. Data were analyzed using one-way Analysis of Variance and Tukey's post-hoc tests (P < .05).

Results: ICON revealed the highest water sorption, solubility mean values (28.90, 7.61) followed by ICON + 0.2 (14.80, 4.82) and ICON + 0.5 (12.32, 0.81) respectively, and vice versa for resin tags penetration. Mineral density of demineralized enamel significantly increased after treatment with ICON + 0.2 and ICON + 0.5.

Conclusion: Incorporation of NS to resin infiltrant decreased its water sorption and solubility along with enhancing the mineral density of the demineralized enamel and the penetration of resin tags.

Keywords: Caries infiltration; Enamel demineralization; Nano-silica; Nanoparticles; Resin infiltrant.

PubMed Disclaimer

Conflict of interest statement

Declarations. Ethics approval and consent to participate: All procedures performed in this study, were carried out in accordance with relevant guidelines and regulations of Helsinki Declarations. The collected premolars were extracted for therapeutic reasons unrelated to the study were collected, with prior informed consent from healthy individuals who were seeking dental care at The Oral and Maxillofacial Surgery Department Clinic, Faculty of Dentistry, Mansoura University. The patients were voluntary donating the extracted teeth to The Faculty for utilizing in research purpose. All the experimental protocols were approved by the Dental Research Ethics Committee of the Faculty of Dentistry, Mansoura University with reference number (A0202024CD). Consent for publication: Not applicable. Competing interests: The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Representative SEM micrographs at × 2,000 magnification showing resin tags penetration measurements for all tested groups; (A) Group I: ICON without NS (control), (B) Group II: ICON with 0.2 wt.% NS, and (C) Group III: ICON with 0.5 wt.% NS
Fig. 2
Fig. 2
A line chart represents the changes in mineral density in all tested groups at the three stages: before demineralization, after caries induction, and after treatment
Fig. 3
Fig. 3
Micro-CT scans of representative enamel surfaces topographies at the three stages: (A) before demineralization, (B) after caries induction, and (C) after treatment, of all tested groups; Group I: ICON without NS (control), Group II: ICON with 0.2 wt.% NS, and Group III: ICON with 0.5 wt.% NS
See this image and copyright information in PMC

References

    1. Wang Q, Zhou Y, Cui T, et al. Comparative evaluation of four treatments for postorthodontic white spot lesions: a randomized controlled trial. Clin Oral Investig. 2023;27(10):5957–68. - PubMed
    1. Singh S, Singh SP, Goyal A, et al. Effects of various remineralizing agents on the outcome of post-orthodontic white spot lesions (WSLs): a clinical trial. Prog Orthod. 2016;17(1):25. - PMC - PubMed
    1. Thirumoorthy SN, Gopal S. White spot enamel lesions - is treatment or prevention the answer to this “no win scenario”? Evid Based Dent. 2024;25(1):51–2. - PubMed
    1. Paris S, Meyer-Lueckel H, Kielbassa AM. Resin infiltration of natural caries lesions. J Dent Res. 2007;86(7):662–6. - PubMed
    1. Paris S, Meyer-Lueckel H, Cölfen H, Kielbassa AM. Resin infiltration of artificial enamel caries lesions with experimental light curing resins. Dent Mater J. 2007;26(4):582–8. - PubMed

LinkOut - more resources