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Review
. 2025 Apr:72 Suppl 2:e31468.
doi: 10.1002/pbc.31468. Epub 2024 Dec 9.

Current Surgical Approach to Pulmonary Metastasectomy

Affiliations
Review

Current Surgical Approach to Pulmonary Metastasectomy

Kristine S Corkum et al. Pediatr Blood Cancer. 2025 Apr.

Abstract

The lung is a common site of metastases for children and adolescents with a wide variety of solid tumors. The role for pulmonary metastasectomy is dictated by tumor histology and can serve either therapeutic or diagnostic purposes. Careful surgical planning is required to determine the optimal surgical approach and to ensure successful nodule localization. While high level data are limited, in appropriate situations pulmonary metastasectomy can confirm staging, guide therapy, improve survival, and reduce the need for other therapy escalations.

Keywords: children; metastasectomy; osteosarcoma; pulmonary metastatic disease; solid tumors.

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References

    1. J. Worch, A. Ranft, S. G. DuBois, M. Paulussen, H. Juergens, and U. Dirksen, “Age Dependency of Primary Tumor Sites and Metastases in Patients With Ewing Sarcoma,” Pediatric Blood & Cancer 65, no. 9 (2018): e27251, https://doi.org/10.1002/pbc.27251.
    1. J. Wang, Y. Fan, and L. Xia, “Lung Metastasis Probability in Ewing Sarcoma: A Nomogram Based on the SEER Database,” Current Oncology 28, no. 1 (2020): 69–77, https://doi.org/10.3390/curroncol28010009.
    1. T. Liu, L. Cui, Z. He, Z. Chen, H. Tao, and J. Yang, “Epidemiology and Nomogram of Pediatric and Young Adulthood Osteosarcoma Patients With Synchronous Lung Metastasis: A SEER Analysis,” PLOS ONE 18, no. 7 (2023): e0288492, https://doi.org/10.1371/journal.pone.0288492.
    1. S. Smeland, S. S. Bielack, J. Whelan, et al., “Survival and Prognosis With Osteosarcoma: Outcomes in More Than 2000 Patients in the EURAMOS‐1 (European and American Osteosarcoma Study) Cohort,” European Journal of Cancer 109 (2019): 36–50, https://doi.org/10.1016/j.ejca.2018.11.027.
    1. A. Briccoli, M. Rocca, M. Salone, G. A. Guzzardella, A. Balladelli, and G. Bacci, “High Grade Osteosarcoma of the Extremities Metastatic to the Lung: Long‐Term Results in 323 Patients Treated Combining Surgery and Chemotherapy, 1985–2005,” Surgical Oncology 19, no. 4 (2010): 193–199, https://doi.org/10.1016/j.suronc.2009.05.002.

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