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Case Reports
. 2025 Mar;69(3):703-707.
doi: 10.1007/s00484-024-02841-z. Epub 2024 Dec 10.

Inhalation therapy with sulfur-rich thermal water for rhinogenic deafness: a series of case reports

Affiliations
Case Reports

Inhalation therapy with sulfur-rich thermal water for rhinogenic deafness: a series of case reports

Michele Antonelli et al. Int J Biometeorol. 2025 Mar.

Abstract

The study analyzed the effectiveness of a two-week cycle of sulfurous water therapy at Frasassi Thermal Springs ("Terme di Frasassi - S. Vittore", located in the Province of Ancona, Italy) on 8 patients suffering from rhinogenic deafness caused by chronic rhinosinusitis associated with nasal polyps and respiratory allergies. Patients underwent 12 sessions of sulfurous aerosol therapy and 12 bilateral tubal insufflations (1 aerosol and 1 insufflation per day). Pre- and post-treatment assessments included tympanometric measurements and a subjective evaluation of symptomatic improvement on a scale from 1 to 10. The median reported improvement was 9.5 (min: 7; max: 10). By the end of the treatment, all patients achieved a bilateral type A/A tympanogram, indicating restored tubal function. The results suggest that sulfurous water thermal therapy can be a useful treatment for rhinogenic deafness associated with chronic rhinosinusitis, nasal polyps, and respiratory allergies, with significant improvements in both auditory function and quality of life. Further studies are needed to compare this treatment with other therapies and to precisely evaluate the duration of the benefit over time.

Keywords: Chronic rhinosinusitis; Hydrothermal therapy; Rhinogenic deafness; Sulfurous waters; Tympanogram.

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Conflict of interest statement

Declarations. Ethics approval: All participants provided informed consent to participate in the study, which was conducted as part of routine clinical care and did not involve the administration of any experimental therapy. Data were fully anonymized in compliance with EU privacy regulations. The study was designed and conducted in full adherence to the principles of the Declaration of Helsinki. Formal ethics committee approval was not required, as the research consisted solely of a series of case reports (Regional Decree: 1104–29/09/2014: “Disposizione concernenti il Comitato Etico Regionale (CER) Regione Marche”). Competing interests: Bruno Borioni, Geniale Mariani, and Marcello Moscoloni serve as physicians at Frasassi Thermal Springs (“Terme di Frasassi - S. Vittore,” AN, Italy). Michele Antonelli acts as an external scientific consultant for the institution. The Administrative Director of Terme di Frasassi had no role in the collection, management, or publication of data related to this work.

References

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