When cell mechanics meets epitranscriptomics: reduction of m6A in Piezo2 RNA ameliorates cardiac fibrosis

Gloria Garoffolo¹, Maurizio Pesce^{1

2

3}

Affiliations

¹ Tissue Engineering Research Unit, Centro Cardiologico Monzino, IRCCS, Via C. Parea, 4, 20138 Milan, Italy.
² Department of Cell Biology, King Faisal Specialist Hospital and Research Center, PO Box 3354, MBC-03 Riyadh 11211, Saudi Arabia.
³ Department of Mechanical and Aerospace Engineering, Corso Duca degli Abruzzi, 2410129 Turin, Italy.

Editorial

Gloria Garoffolo et al. Cardiovasc Res. 2024.

. 2024 Dec 31;120(17):2158-2159.

doi: 10.1093/cvr/cvae247.

Gloria Garoffolo¹, Maurizio Pesce^{1

2

3}

¹ Tissue Engineering Research Unit, Centro Cardiologico Monzino, IRCCS, Via C. Parea, 4, 20138 Milan, Italy.
² Department of Cell Biology, King Faisal Specialist Hospital and Research Center, PO Box 3354, MBC-03 Riyadh 11211, Saudi Arabia.
³ Department of Mechanical and Aerospace Engineering, Corso Duca degli Abruzzi, 2410129 Turin, Italy.

No abstract available

Conflict of interest statement

Conflict of interest: none declared.

Epitranscriptomic regulation of cardiac fibrosis via YTHDF1-dependent PIEZO2 mRNA m6A modification.
Ding JF, Tu B, Song K, Liu ZY, Lin LC, Liu ZY, Shi Y, Yang JJ, Zhao JY, Tao H. Ding JF, et al. Cardiovasc Res. 2024 Dec 31;120(17):2236-2248. doi: 10.1093/cvr/cvae239. Cardiovasc Res. 2024. PMID: 39498803