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. 2024 Dec;45(12):1318-1325.
doi: 10.15537/smj.2024.45.12.20240645.

Feasibility and safety of a cable transmission magnetically controlled capsule endoscopy system for examination of the human upper digestive tract

Hang Yu  1 , Yuan Tian  1 , Long Rong  1 , Yunlong Cai  1 , Guanyi Liu  1 , Yan He  1 , Xinyue Guo  1
Affiliations

Feasibility and safety of a cable transmission magnetically controlled capsule endoscopy system for examination of the human upper digestive tract

Hang Yu et al. Saudi Med J. 2024 Dec.

Abstract

Objectives: To evaluate the safety and feasibility of the cable-transmitted, magnetically controlled capsule endoscopy (CT-MCCE) system for examining the esophagus and stomach.

Methods: A pilot study was carried out at the endoscopy facility of Peking University First Hospital; 30 volunteers were enrolled between September and November 2022. All participants were instructed to swallow the CT-MCCE capsule. An external magnetic robot arm was utilized to manipulate the capsule endoscope with string-facilitated control of the endoscope. This study assessed gastric preparation, safety, maneuverability, and mucosal visualization.

Results: The participants exhibited favorable reactions to the gastric preparation and examination, with no reported adverse effects, and the average duration of the gastric examination was 29.5±6.63 minutes. The gastric cavity cleanliness assessment revealed a good rating in 25 participants (83.3%) and a moderate rating in 5 participants (11.8%). TheCT-MCCE demonstrated good maneuverability in all 30 subjects (100%).The analysis of visualization indicated that more than 75% of the gastric mucosa was discerned in 79.4% of the participants (27 individuals), whereas 50% to 75% was visualized in 20.6% of the participants (7 individuals).

Conclusion: This study substantiates the feasibility and safety of employing magnetically controlled capsule endoscopy with cable transmission for the evaluation of human stomach and esophagus.

Keywords: cable transmission; feasibility; magnetically controlled capsule endoscopy; safety; upper gastrointestinal examination.

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Figures

Figure 1
Figure 1
- The Cable Transmission Magnetically Controlled Capsule Endoscope system. A) Disposable sterile capsule endoscope. B) The Image Processor. C) The front view of the magnetic-controlled capsule system.
Figure 2
Figure 2
- The images of primary landmarks in esophagus and stomach. A) esophagus, B) dentate line, C) cardia, D) fundus, E) body of stomach, F) angulus, G) antrum, H) pylorus
Figure 3
Figure 3
- The total visualization score distribution of 30 volunteers.
Figure 4
Figure 4
- Gastric polyps and reflux esophagitis were found during Cable transmission Magnetically Controlled Capsule Endoscope examination. A) The image of gastric polypsby capsule endoscope. B) gastric polyps confirmed by the following gastroscopy. C) The image ofreflux esophagitisby capsule endoscope. D) reflux esophagitis confirmed by the following gastroscopy.
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