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. 2024 Dec 9;42(12):1993-1996.
doi: 10.1016/j.ccell.2024.11.001.

Molecular subtyping in urothelial carcinoma treatment

Xiaowen Wu  1 , Xinan Sheng  2
Affiliations

Molecular subtyping in urothelial carcinoma treatment

Xiaowen Wu et al. Cancer Cell. .

Abstract

The heterogeneity of urothelial carcinoma (UC) and variable treatment responses poses significant clinical challenges. In this issue of Cancer Cell, Hamidi et al. conducted a multi-omics analysis of 2,803 UC patients from four clinical trials with anti-PD-L1, revealing four transcriptional subtypes. This approach could help tailor therapies for UC.

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Conflict of interest statement

Declaration of interests X.S. has the following potential conflicts of interest to disclose: non-profit consultant for Pfizer, Novartis, Astellas, AstraZeneca, Bayer, MSD, RemeGen, and Junshi Biosciences.

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