Allogeneic hematopoietic stem cell transplantation in adult acute myeloid leukemia with t(16;21)(p11;q22)/FUS::ERG

Satoshi Mitsuyuki¹, Yoshimitsu Shimomura^{2

3}, Hiroki Mizumaki⁴, Masamitsu Yanada⁵, Shohei Mizuno⁶, Naoyuki Uchida⁷, Noriko Doki⁸, Ayumu Ito⁹, Masatsugu Tanaka¹⁰, Tetsuya Nishida¹¹, Yuta Katayama¹², Satoshi Yoshihara¹³, Tetsuya Eto¹⁴, Satoru Takada¹⁵, Shuichi Ota¹⁶, Masako Toyosaki¹⁷, Yuta Hasegawa¹⁸, Hirohisa Nakamae¹⁹, Koji Kawamura²⁰, Makoto Onizuka¹⁷, Takahiro Fukuda⁹, Marie Ohbiki^{21

22

23}, Yoshiko Atsuta^{21

22}, Takaaki Konuma²⁴

Affiliations

¹ Department of Hematology, Kobe City Medical Center General Hospital, Kobe, Japan. mitsuyuki0402@gmail.com.
² Department of Hematology, Kobe City Medical Center General Hospital, Kobe, Japan.
³ Department of Environmental Medicine and Population Science, Graduate School of Medicine, Osaka University, Osaka, Japan.
⁴ Department of Hematology, Kanazawa University, Kanazawa, Japan.
⁵ Department of Hematology and Oncology, Nagoya City University East Medical Center, Nagoya, Japan.
⁶ Division of Hematology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Japan.
⁷ Department of Hematology, Federation of National Public Service Personnel Mutual Aid Associations, Toranomon Hospital, Tokyo, Japan.
⁸ Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.
⁹ Department of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
¹⁰ Department of Hematology, Kanagawa Cancer Center, Yokohama, Japan.
¹¹ Department of Hematology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, Japan.
¹² Department of Hematology, Hiroshima Red Cross Hospital & Atomic-Bomb Survivors Hospital, Hiroshima, Japan.
¹³ Department of Hematology, Hyogo Medical University Hospital, Nishinomiya, Japan.
¹⁴ Department of Hematology, Hamanomachi Hospital, Fukuoka, Japan.
¹⁵ Leukemia Research Center, Saiseikai Maebashi Hospital, Maebashi, Japan.
¹⁶ Department of Hematology, Sapporo Hokuyu Hospital, Sapporo, Japan.
¹⁷ Department of Hematology and Oncology, Tokai University School of Medicine, Isehara, Japan.
¹⁸ Department of Hematology, Hokkaido University Hospital, Sapporo, Japan.
¹⁹ Department of Hematology, Osaka Metropolitan University Hospital, Osaka, Japan.
²⁰ Division of Clinical Laboratory Medicine, Department of Multidisciplinary Internal Medicine, Tottori University, Tottori, Japan.
²¹ Japanese Data Center for Hematopoietic Cell Transplantation, Nagakute, Japan.
²² Department of Registry Science for Transplant and Cellular Therapy, Aichi Medical University School of Medicine, Nagakute, Japan.
²³ Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
²⁴ Department of Hematology/Oncology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

PMID: 39658629
DOI: 10.1038/s41375-024-02495-1

Allogeneic hematopoietic stem cell transplantation in adult acute myeloid leukemia with t(16;21)(p11;q22)/FUS::ERG

Satoshi Mitsuyuki et al. Leukemia. 2025 Feb.

. 2025 Feb;39(2):495-498.

doi: 10.1038/s41375-024-02495-1. Epub 2024 Dec 10.

Authors

Affiliations

¹ Department of Hematology, Kobe City Medical Center General Hospital, Kobe, Japan. mitsuyuki0402@gmail.com.
² Department of Hematology, Kobe City Medical Center General Hospital, Kobe, Japan.
³ Department of Environmental Medicine and Population Science, Graduate School of Medicine, Osaka University, Osaka, Japan.
⁴ Department of Hematology, Kanazawa University, Kanazawa, Japan.
⁵ Department of Hematology and Oncology, Nagoya City University East Medical Center, Nagoya, Japan.
⁶ Division of Hematology, Department of Internal Medicine, Aichi Medical University School of Medicine, Nagakute, Japan.
⁷ Department of Hematology, Federation of National Public Service Personnel Mutual Aid Associations, Toranomon Hospital, Tokyo, Japan.
⁸ Hematology Division, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.
⁹ Department of Hematopoietic Stem Cell Transplantation, National Cancer Center Hospital, Tokyo, Japan.
¹⁰ Department of Hematology, Kanagawa Cancer Center, Yokohama, Japan.
¹¹ Department of Hematology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, Japan.
¹² Department of Hematology, Hiroshima Red Cross Hospital & Atomic-Bomb Survivors Hospital, Hiroshima, Japan.
¹³ Department of Hematology, Hyogo Medical University Hospital, Nishinomiya, Japan.
¹⁴ Department of Hematology, Hamanomachi Hospital, Fukuoka, Japan.
¹⁵ Leukemia Research Center, Saiseikai Maebashi Hospital, Maebashi, Japan.
¹⁶ Department of Hematology, Sapporo Hokuyu Hospital, Sapporo, Japan.
¹⁷ Department of Hematology and Oncology, Tokai University School of Medicine, Isehara, Japan.
¹⁸ Department of Hematology, Hokkaido University Hospital, Sapporo, Japan.
¹⁹ Department of Hematology, Osaka Metropolitan University Hospital, Osaka, Japan.
²⁰ Division of Clinical Laboratory Medicine, Department of Multidisciplinary Internal Medicine, Tottori University, Tottori, Japan.
²¹ Japanese Data Center for Hematopoietic Cell Transplantation, Nagakute, Japan.
²² Department of Registry Science for Transplant and Cellular Therapy, Aichi Medical University School of Medicine, Nagakute, Japan.
²³ Department of Hematology and Oncology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
²⁴ Department of Hematology/Oncology, The Institute of Medical Science, The University of Tokyo, Tokyo, Japan.

PMID: 39658629
DOI: 10.1038/s41375-024-02495-1

No abstract available

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Conflict of interest statement

Ethics approval and consent to participate: This study was approved by the Japanese Data Center for Hematopoietic Cell Transplantation and the Institutional Review Board of Kobe City Medical Center General Hospital and conducted in accordance with the Declaration of Helsinki (approval number: zn240506). Written informed consent was obtained from each patient at each institution before Transplant Registry Unified Management Program 2 registration. Competing interests: Shohei Mizuno received research funding from Hayashikane Sangyo and lecture fees from Janssen Pharmaceutical. The other authors declare no conflicts of interest associated with this manuscript.

References

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1. Zhou Z, Zhuo N, Zhou Y, Sun C, Yao Y, Mao L, et al. Identification of the characteristics and prognostic impact of FUS::ERG and RUNX1::CBFA2T3 fusion genes in adult acute myeloid leukemia patients. Am J Hematol. 2024;99:1441–4. - DOI - PubMed
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Allogeneic hematopoietic stem cell transplantation in adult acute myeloid leukemia with t(16;21)(p11;q22)/FUS::ERG

Affiliations

Allogeneic hematopoietic stem cell transplantation in adult acute myeloid leukemia with t(16;21)(p11;q22)/FUS::ERG

Authors

Affiliations

Conflict of interest statement

References

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