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. 2025 Jan;51(1):179-181.
doi: 10.1007/s00134-024-07718-8. Epub 2024 Dec 12.

Effects of delayed consent on patient characteristics in adult patients with sepsis

Frank Bloos  1 , Holger Bogatsch  2 , Mihai G Netea  3   4 , Evangelos J Giamarellos-Bourboulis  5 , Michael Bauer  6 ; SepNet Critical Care Trials Group
Collaborators, Affiliations

Effects of delayed consent on patient characteristics in adult patients with sepsis

Frank Bloos et al. Intensive Care Med. 2025 Jan.
No abstract available

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Figures

Fig. 1
Fig. 1
Kaplan–Meier curve for survival within 28 days after study inclusion stratified by the ability to give informed consent. Log-rank test: p < 0.001
See this image and copyright information in PMC

References

    1. Fost N, Robertson JA (1980) Deferring consent with incompetent patients in an intensive care unit. IRB 2:5–6 - PubMed
    1. van der Graaf R, Hoogerwerf M-A, de Vries MC (2020) The ethics of deferred consent in times of pandemics. Nat Med 26:1328–1330 - PubMed
    1. Brunkhorst FM, Oppert M, Marx G et al (2012) Effect of empirical treatment with moxifloxacin and meropenem vs meropenem on sepsis-related organ dysfunction in patients with severe sepsis: a randomized trial. JAMA 307:2390–2399 - PubMed
    1. Bloos F, Trips E, Nierhaus A et al (2016) Effect of sodium selenite administration and procalcitonin-guided therapy on mortality in patients with severe sepsis or septic shock: a randomized clinical trial. JAMA Intern Med 176:1266–1276 - PubMed
    1. Bloos F, Held J, Kluge S et al (2022) (1 → 3)-β-D-Glucan-guided antifungal therapy in adults with sepsis: the CandiSep randomized clinical trial. Intensive Care Med 48:865–875 - PMC - PubMed

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