Performance of serum IL-18 levels for the follow-up of patients with familial Mediterranean fever

Inès Elhani¹, Laure Calas², Farah Bejar², Laurence Pieroni³, Isabelle Kone-Paut⁴, Linda Rossi-Semerano⁴, Isabelle Melki⁵, Brigitte Bader-Meunier⁶, Bénédicte Neven⁶, Pierre Quartier⁶, Guilaine Boursier⁷, Irina Giurgea⁸, Laurence Cuisset⁹, Gilles Grateau¹⁰, Véronique Hentgen¹¹, Philippe Mertz¹², Marion Delplanque¹², Léa Savey¹², Sophie Georgin-Lavialle¹³

Affiliations

¹ Department of Internal Medicine, Tenon Hospital, DMU 3ID, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France; CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France. Electronic address: ines.elhani@aphp.fr.
² Department of Biochemistry, Tenon Hospital, DMU BioGemH, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France; INSERM, UMRS 1155 UPMC, hôpital Tenon, Paris, France.
³ Department of Biochemistry, Tenon Hospital, DMU BioGemH, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France.
⁴ CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France; ERN RITA-European Reference Network for Rare Immunodeficiency, Autoinflammatory, and Autoimmune Diseases, Utrecht, Netherland; Pediatric Rheumatology Department, Kremlin Bicêtre Hospital, AP-HP, Le Kremlin Bicêtre, Paris Saclay University, Paris, France.
⁵ Department of General Pediatrics, Armand Trousseau Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne Université, Paris, France; Reference Center for Rheumatic, AutoImmune and Systemic Diseases in Children (RAISE), General Pediatrics, Infectious Disease and Internal Medicine Department, Hôpital Robert Debre, AP-HP, Paris, France.
⁶ ERN RITA-European Reference Network for Rare Immunodeficiency, Autoinflammatory, and Autoimmune Diseases, Utrecht, Netherland; Reference Center for Rheumatic, AutoImmune and Systemic Diseases in Children (RAISE), General Pediatrics, Infectious Disease and Internal Medicine Department, Hôpital Robert Debre, AP-HP, Paris, France; Pediatric Immunology, Hematology and Rheumatology Department, Necker Hospital, AP-HP, Paris, France.
⁷ CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France; Department of Molecular Genetics and Cytogenomics, Rare and Auto Inflammatory Diseases Unit, CHU Montpellier, University of Montpellier, Montpellier, France.
⁸ Genetic Department, Trousseau Hospital, AP-HP, Paris, France.
⁹ Genetic Department, Cochin Hospital, AP-HP, Paris, France.
¹⁰ Department of Internal Medicine, Tenon Hospital, DMU 3ID, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France.
¹¹ CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France; Department of Pediatrics, Versailles Hospital, Le Chesnay, France.
¹² Department of Internal Medicine, Tenon Hospital, DMU 3ID, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France; CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France.
¹³ Department of Internal Medicine, Tenon Hospital, DMU 3ID, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France; CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France; INSERM, UMRS 1155 UPMC, hôpital Tenon, Paris, France; INSERM U938, Paris, France. Electronic address: Sophie.georgin-lavialle@aphp.fr.

PMID: 39667435
DOI: 10.1016/j.jaip.2024.11.025

Free article

Performance of serum IL-18 levels for the follow-up of patients with familial Mediterranean fever

Inès Elhani et al. J Allergy Clin Immunol Pract. 2025 Mar.

Free article

. 2025 Mar;13(3):695-697.e1.

doi: 10.1016/j.jaip.2024.11.025. Epub 2024 Dec 10.

Authors

Affiliations

¹ Department of Internal Medicine, Tenon Hospital, DMU 3ID, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France; CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France. Electronic address: ines.elhani@aphp.fr.
² Department of Biochemistry, Tenon Hospital, DMU BioGemH, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France; INSERM, UMRS 1155 UPMC, hôpital Tenon, Paris, France.
³ Department of Biochemistry, Tenon Hospital, DMU BioGemH, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France.
⁴ CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France; ERN RITA-European Reference Network for Rare Immunodeficiency, Autoinflammatory, and Autoimmune Diseases, Utrecht, Netherland; Pediatric Rheumatology Department, Kremlin Bicêtre Hospital, AP-HP, Le Kremlin Bicêtre, Paris Saclay University, Paris, France.
⁵ Department of General Pediatrics, Armand Trousseau Hospital, Assistance Publique-Hôpitaux de Paris (AP-HP), Sorbonne Université, Paris, France; Reference Center for Rheumatic, AutoImmune and Systemic Diseases in Children (RAISE), General Pediatrics, Infectious Disease and Internal Medicine Department, Hôpital Robert Debre, AP-HP, Paris, France.
⁶ ERN RITA-European Reference Network for Rare Immunodeficiency, Autoinflammatory, and Autoimmune Diseases, Utrecht, Netherland; Reference Center for Rheumatic, AutoImmune and Systemic Diseases in Children (RAISE), General Pediatrics, Infectious Disease and Internal Medicine Department, Hôpital Robert Debre, AP-HP, Paris, France; Pediatric Immunology, Hematology and Rheumatology Department, Necker Hospital, AP-HP, Paris, France.
⁷ CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France; Department of Molecular Genetics and Cytogenomics, Rare and Auto Inflammatory Diseases Unit, CHU Montpellier, University of Montpellier, Montpellier, France.
⁸ Genetic Department, Trousseau Hospital, AP-HP, Paris, France.
⁹ Genetic Department, Cochin Hospital, AP-HP, Paris, France.
¹⁰ Department of Internal Medicine, Tenon Hospital, DMU 3ID, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France.
¹¹ CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France; Department of Pediatrics, Versailles Hospital, Le Chesnay, France.
¹² Department of Internal Medicine, Tenon Hospital, DMU 3ID, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France; CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France.
¹³ Department of Internal Medicine, Tenon Hospital, DMU 3ID, Sorbonne Université-Assistance Publique Hôpitaux de Paris, Paris, France; CEREMAIA (National reference center for autoinflammatory diseases ad AA amyloidosis), Paris, France; INSERM, UMRS 1155 UPMC, hôpital Tenon, Paris, France; INSERM U938, Paris, France. Electronic address: Sophie.georgin-lavialle@aphp.fr.