Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Oct;66(10):973-977.
doi: 10.4103/indianjpsychiatry.indianjpsychiatry_222_24. Epub 2024 Oct 17.

Experience of using electroconvulsive therapy for bipolar disorder: A retrospective study from North India

Affiliations

Experience of using electroconvulsive therapy for bipolar disorder: A retrospective study from North India

Sandeep Grover et al. Indian J Psychiatry. 2024 Oct.

Abstract

Background: Little information is available on response to electroconvulsive therapy (ECT) in patients with bipolar disorder (BD) from India.

Aim: This exploratory study aims to evaluate and compare the sociodemographic and clinical profiles, treatment outcomes of BD patients with depression and mania/mixed episode who received ECT and to evaluate the predictors of response to ECT.

Results: Data of 278 BD patients who received 325 ECT courses were extracted from the ECT register. The number courses of ECT for bipolar depression (n = 202) exceeded those for mania/mixed episodes (n = 123). In terms of response to ECT, >75% response was achieved in 63.3% cases and >50% response was seen in about 90% of the patients. No significant difference was seen in response to ECTs between bipolar depression and mania/mixed episodes.

Conclusion: The present study suggests that about two-thirds of the BD patients show more than 75% response to ECT, and more than 90% of the BD patients show more than 50% response to ECT.

Keywords: Bipolar disorder; depressive episode; electroconvulsive therapy; manic episode; treatment response.

PubMed Disclaimer

Conflict of interest statement

There are no conflicts of interest.

Similar articles

References

    1. Yatham LN, Kennedy SH, Parikh SV, Schaffer A, Bond DJ, Frey BN, et al. Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder. Bipolar Disord. 2018;20:97–170. - PMC - PubMed
    1. Malhi GS, Bell E, Boyce P, Bassett D, Berk M, Bryant R, et al. The 2020 Royal Australian and New Zealand College of psychiatrists clinical practice guidelines for mood disorders: Bipolar disorder summary. Bipolar Disord. 2020;22:805–21. - PubMed
    1. Reddy YJ, Jhanwar V, Nagpal R, Reddy MS, Shah N, Ghorpade S, et al. Prescribing practices of Indian psychiatrists in the treatment of bipolar disorder. Aust N Z J Psychiatry. 2019;53:458–69. - PubMed
    1. Bouali W, Gniwa RO, Soussia RB, Mohamed AH, Zarrouck L. Clinical profile and outcome of bipolar disorder patients receiving electroconvulsive therapy. Eur Psychiatry. 2021;64(S1):S198–9.
    1. Dierckx B, Heijnen WT, van den Broek WW, Birkenhäger TK. Efficacy of electroconvulsive therapy in bipolar versus unipolar major depression: A meta-analysis. Bipolar Disord. 2012;14:146–50. - PubMed

LinkOut - more resources