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Case Reports
. 2024 Oct 2:28:212-215.
doi: 10.1016/j.xjtc.2024.09.023. eCollection 2024 Dec.

Radiation-induced dedifferentiated chondrosarcoma of the chest wall

Ira Goldsmith  1 , Maurizio Brotto  2 , Thomas Bragg  3
Affiliations
Case Reports

Radiation-induced dedifferentiated chondrosarcoma of the chest wall

Ira Goldsmith et al. JTCVS Tech. .
No abstract available

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Conflict of interest statement

The authors reported no conflicts of interest. The Journal policy requires editors and reviewers to disclose conflicts of interest and to decline handling or reviewing manuscripts for which they may have a conflict of interest. The editors and reviewers of this article have no conflicts of interest.

Figures

None
Dedifferentiated chondrosarcoma of the chest.
Figure 1
Figure 1
Planning of surgical resection and reconstruction. A, Segmentation: Three-dimensional (3D) image of the tumor and chest wall was created with Mimics Medical software. B, Editing: The tumor was grown by 2× cm to determine all-around clear surgical margins. C, Fabrication of custom-made, anatomic 3D-printed ribs 3, 4, and 5 implants. Designed using Geomagic Freeform Plus software and 3D manufactured in titanium with direct metal laser sintering.
Figure 2
Figure 2
Histology with hematoxylin and eosin staining and 10× magnification showing nonosseous hyaline cartilage (A) and absence of hyaline cartilage (B), with a solid stroma composed of a proliferation of atypical spindle cells (mesenchymal cells) (arrow). (C) Dedifferentiated component with a pleomorphic proliferation of highly atypical mesenchymal cells with atypical mitoses (arrow). (D) Immunohistochemistry: Negative cytokeratin expression highlights the absence of the epithelial component.
See this image and copyright information in PMC

References

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E-References

    1. Goldsmith I., Dovgalski L., Evans P.L. 3D printing technology for chest wall reconstruction with a sternum-ribs-cartilage titanium implant: from ideation to creation. Innovations (Phila) 2023;18(1):67–72. - PubMed
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