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. 2025 Feb;20(2):151-165.
doi: 10.1177/17474930241309276. Epub 2025 Jan 3.

World Stroke Organization and World Hypertension League position statement on hypertension control strategies in prevention and management of stroke

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World Stroke Organization and World Hypertension League position statement on hypertension control strategies in prevention and management of stroke

Jeyaraj Durai Pandian et al. Int J Stroke. 2025 Feb.

Abstract

Background and purpose: The goal of this consensus is to provide a comprehensive set of recommendations in regard to hypertension control strategies for the prevention and management of stroke. This document is intended for prehospital care providers, physicians, allied health professionals, and hospital administrators and healthcare policymakers.

Methods: Members of the writing group were representatives of the World Stroke Organization and World Hypertension League. The writing group reviewed articles searched from PubMed and Google Scholar using selected search strings. The document was sent to 12 peer reviewers. The writing group considered the feedback from peer reviewers and made revisions accordingly. Every member of the writing group gave their approval of the final document.

Results: This article details the various techniques for blood pressure (BP) measurement, BP classification, BP and stroke risk, antihypertensive drug therapy for the primary and secondary prevention of stroke, choice of antihypertensive drug therapy, optimal BP targets, non-drug approaches to the prevention of stroke through BP lowering, BP management separately for acute ischemic stroke and spontaneous intracerebral hemorrhage, and the implementation of BP prevention, treatment, and control in the community.

Conclusion: This article provides general recommendations based on currently available evidence to guide healthcare practitioners caring for adults with hypertension for the prevention and management of stroke. Future studies are needed to better define approaches to hypertension control in the community and high-risk groups.

Keywords: Stroke; hemorrhagic stroke; hypertension; ischemic stroke; prevention.

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Conflict of interest statement

Declaration of conflicting interestThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: S.O.M. declares receiving research funding from the Ministry of Health of Brazil/Hospital Moinhos de Vento through the PROADI-SUS Program to PROMOTE Trial, RESILIENT Direct TNK, RESILIENT Extend IV, and TRIDENT and declares receiving honoraria as a speaker from Boehringer Ingelheim, Medtronic, Penumbra, Novartis, Novo Nordisk, and Servier.

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