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Review
. 2025 Apr;20(3):643-654.
doi: 10.1007/s11739-024-03835-w. Epub 2024 Dec 13.

Diaphragmatic ultrasound: approach, emerging evidence, and future perspectives in non-ICU patients

Affiliations
Review

Diaphragmatic ultrasound: approach, emerging evidence, and future perspectives in non-ICU patients

Sigmund J Kharasch et al. Intern Emerg Med. 2025 Apr.

Abstract

Diaphragmatic dysfunction is an important contributor to hypercapnic respiratory failure, but its presence is often challenging to determine at the bedside. Diaphragm ultrasound provides an opportunity to evaluate the function of the diaphragm noninvasively by evaluating the following parameters that can help define diaphragmatic dysfunction: diaphragm excursion, diaphragm muscle thickness, and thickening fraction. Its evaluation has the potential to assist with diagnosis of respiratory failure, provide prognosis, and assist with patient monitoring and should be considered as part of an internal medicine physician's and emergency physician's skill set. This article provides an overview on how to perform diaphragm ultrasound, review its pitfalls, and discuss the evidence of its use in patients with neuromuscular disorders and chronic obstructive pulmonary disease. Finally, its potential emerging uses in the perioperative setting and for evaluation of acute heart failure are discussed.

Keywords: Diaphragm; Diaphragm ultrasound; Diaphragmatic dysfunction; Diaphragmatic excursion; Point-of-care-ultrasound; Respiratory failure.

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Conflict of interest statement

Declarations. Conflict of interest: I.M. is funded as a Research Chair holder (John A. Buchanan Chair in General Internal Medicine) at the University of Calgary. The remaining authors declare that they have no conflict of interest. Human and animal rights: This article does not directly involve human participants, as it is a review of published data. Informed consent: Not applicable.

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