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Observational Study
. 2024 Dec 9:19:2071-2083.
doi: 10.2147/CIA.S472579. eCollection 2024.

Impact of Obesity on Clinical Presentation and Surgical Outcomes in Patients with Benign Prostate Hyperplasia Receiving Greenlight Laser Prostatectomy

Po-Han Chen #  1 , Ruei-Je Chang #  2 , Hsiang-Sheng Wang  3 , Ying-Hsu Chang  4   5 , Chung-Yi Liu  4   5 , Liang-Kang Huang  2   4 , Hung-Chen Kan  2   4 , Po-Hung Lin  2   4 , Kai-Jie Yu  2   4 , Cheng-Keng Chuang  2   4 , See-Tong Pang  2   4 , Chun-Te Wu  2   4 , Ming-Li Hsieh  2   4 , I-Hung Shao  2   4
Affiliations
Observational Study

Impact of Obesity on Clinical Presentation and Surgical Outcomes in Patients with Benign Prostate Hyperplasia Receiving Greenlight Laser Prostatectomy

Po-Han Chen et al. Clin Interv Aging. .

Abstract

Objective: To investigate the impact of body mass index (BMI) on preoperative characteristics, lower urinary tract symptoms (LUTS), intraoperative variables, surgical outcomes and postoperative complications.

Methods: This is a retrospective observational study including 891 benign prostate hyperplasia (BPH) patients who underwent GreenLight Laser photoselective vaporization of the prostate (PVP) between 2014 and 2020. Clinical characteristics, uroflowmetry parameters, and surgery related parameters were extracted from electronic health records. Patients were categorized into different weight groups based on Taiwanese populations' BMI criteria. Statistical analyses, involving descriptive statistics, correlation analyses, and independent t-tests, were employed to examine associations between BMI and relevant variables.

Results: Pearson's correlation analysis indicated a negative correlation between BMI (r = -0.172, p < 0.001) and age, and positive correlations with total prostate volume (TPV) (r = 0.123, p < 0.001) and transition zone volume (TZV) (r = 0.083, p = 0.017). Obese patients were found to be younger (p=0.007) and have larger TPVs (p=0.010) but showed no significant differences in International Prostate Symptom Scores (IPSS) scores when compared to non-obese patients. Notably, obese patients had lower preoperative and postoperative post-void residual (PVR), whereas non-obese patients exhibited a more significant PVR reduction post-surgery. BMI did not significantly affect surgical parameters or postoperative complications.

Conclusion: In BPH patients treated with PVP, obese individuals were younger with larger prostates but had similar IPSS scores compared to non-obese patients. Obese patients had lower pre and post-surgery PVR, while non-obese patients saw greater PVR improvements. BMI plays a nuanced role BPH patients' characteristics.

Keywords: GreenLight Laser; benign prostate hyperplasia; body mass index; functional study; photoselective vaporization of the prostate; urodynamic study.

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Conflict of interest statement

The authors declare that they have no competing interests.

Figures

Figure 1
Figure 1
Post-voiding residual change after surgery of all participants.
None
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References

    1. Chughtai B, Forde JC, Thomas DDM, et al. Benign prostatic hyperplasia. Nat Rev Dis Primers. 2016;2:16031. doi:10.1038/nrdp.2016.31 - DOI - PubMed
    1. Teng J, Zhang D, Li Y, et al. Photoselective vaporization with the green light laser vs transurethral resection of the prostate for treating benign prostate hyperplasia: a systematic review and meta-analysis. BJU Int. 2013;111(2):312–323. doi:10.1111/j.1464-410X.2012.11395.x - DOI - PubMed
    1. Schwartz RN, Couture F, Sadri I, et al. Reasons to believe in vaporization: a review of the benefits of photo-selective and transurethral vaporization. World J Urol. 2021;39(7):2263–2268. doi:10.1007/s00345-020-03447-x - DOI - PubMed
    1. World Health Organization. Obesity; [cited 2024 January 11,]. Available from: https://www.who.int/health-topics/obesity#tab=tab_1.Accessed November 18, 2024.
    1. Collaboration NCDRF. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million participants. Lancet. 2016;387(10026):1377–1396. - PMC - PubMed

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