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. 2024 Dec 16;52(6):207-212.
doi: 10.4274/TJAR.2024.241676.

The Anticipated Organ Donation Approach Increases the Number of Organ Donors

Erwan d'Aranda  1 , Valérie Arsonneau  2 , Didier Demory  2   3
Affiliations

The Anticipated Organ Donation Approach Increases the Number of Organ Donors

Erwan d'Aranda et al. Turk J Anaesthesiol Reanim. .

Abstract

Objective: Deficiency of organs for transplantation is a significant public health issue. French learned societies accept intensive care unit admission for patients with catastrophic neurological prognosis to optimize organs prior to probable brain death. We evaluated the implementation of a specific ethical care procedure for these patients.

Methods: A descriptive before-after study was conducted, comparing the 2009-2012 period to the 2013-2016 period, during which this procedure was applied.

Results: The number of patients increased from 145 to 186 (+28.3%) and the number of harvested organs increased from 323 to 485 (+50.1%). The anticipated organ donation approach was initiated 135 times. Of the 117 meetings with families, 83 (71%) consented to organ donation. Fifty-three (64%) patients were brain dead, and 49 (92%) of these patients had 194 organs harvested.

Conclusion: The anticipated approach increased the number of donors and organs suitable for grafts. The application of a specific protocol for managing untreatable catastrophic neurological patients improved communication between hospital staff and families and respected patient autonomy by offering options for either organ donation or palliative care.

Keywords: Brain death; intensive care; organ donors; organ procurement; tissue donors.

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Conflict of interest statement

Declaration of Interests: The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Step-by-step screening of a patient with catastrophic brain injury.
Figure 2
Figure 2
Number of renal grafts per year.
Figure 3
Figure 3
Flow chart of patient evolution with an anticipated organ donation approach during the 2013-2016 period. ICU, intensive care unit; OPO, organ procurement organization
See this image and copyright information in PMC

References

    1. Citerio G, Cypel M, Dobb GJ, et al. Organ donation in adults: a critical care perspective. Intensive Care Med. 2016;42(3):305-315. - PubMed
    1. Ministère du travail, de la santé, et des solidarités. Greffes et dons d’organes : plans d’actions 2022-2026. Ministère du travail, de la santé, et des solidarités. Published on July 15, 2024. Accessed July 15, 2024. https://sante.gouv.fr/soins-et-maladies/autres-produits-de-sante/article....
    1. Metzger RA, Delmonico FL, Feng S, Port FK, Wynn JJ, Merion RM. Expanded criteria donors for kidney transplantation. Am J Transplant. 2003;3(Suppl 4):114–125. - PubMed
    1. Agence de la biomédecine. Le rapport médical et scientifique 2022. Published September 17, 2023. Accessed on July 15, 2024. https://www.agence-biomedecine.fr/Le-rapport-medicalet-scientifique-2022...
    1. Bollaert PE, Vinatier I, Orlikowski D, Meyer P. Stroke management by intensivist in adults and children (subarachnoid hemorrhage excluded, new-born excluded). Société de réanimation de langue francaise experts recommendations. Réanimation. 2010;19(6):471–478.

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