Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2025 Jan 20;138(2):185-192.
doi: 10.1097/CM9.0000000000003416. Epub 2024 Dec 17.

Recent global patterns in skin cancer incidence, mortality, and prevalence

Mingyue Wang  1   2   3   4 , Xinghua Gao  1   2   3   4 , Li Zhang  1   2   3   4
Affiliations

Recent global patterns in skin cancer incidence, mortality, and prevalence

Mingyue Wang et al. Chin Med J (Engl). .

Abstract

Background: Skin cancer is a common skin disease whose incidence and mortality rates have been showing yearly increases. In this report, we update the most recent data on skin cancer as obtained from GLOBOCAN 2022.

Methods: The incidence and mortality rates of skin cancer (melanoma of skin and non-melanoma skin cancer) in GLOBOCAN 2022 were reviewed. These data were analyzed and the characteristics of incidence and mortality across five continents and top five countries and regions in each continent are presented. In addition, correlations between Human Development Index (HDI) and age-standardized incidence and mortality rates of these two skin cancers are described.

Results: The GLOBOCAN 2022 data indicated that melanoma was the 17th most common cancer. An estimated 331,722 people were diagnosed with melanoma globally and approximately 58,667 died from this disease. For non-melanoma skin cancer, it ranks as the 5th most common cancer, and an estimated 1,234,533 people were diagnosed with non-melanoma skin cancer globally and approximately 69,416 died from this disease. The incidence of skin cancer varies across geographic regions and countries, with a predominance observed in Oceania, North America, and Europe. Australia was ranked first in terms of incidence, while incidence rates in Africa and Asia were very low. Despite these regional differences in incidence, there was little geographic variation in mortality rates. Currently, the number of deaths from non-melanoma skin cancer exceeds that of melanoma of skin. HDI was positively associated with the incidence of both types of skin cancers, with a positive correlation obtained between HDI and mortality from melanoma of skin and a negative correlation between HDI and mortality from non-melanoma skin cancer.

Conclusions: Skin cancer remains a major disease burden worldwide. Substantial variations are observed across countries and regions. Further research on skin cancer will be required to provide a rationale for more effective preventions and treatments of this condition.

PubMed Disclaimer

Conflict of interest statement

This research was supported by the grants from the National Key R&D Program of China (No. 2023YFC2508200), National Natural Science Foundation of China (No. 82273538), and the Public Health Research and Development Program of the Shenyang Science and Technology Bureau (No. 22-321-33-12).

None

Figures

Figure 1
Figure 1
Prevalence of melanoma (A) and non-melanoma skin cancer (B) in five continents with the 1-year, 3-year, and 5-year analyses based on data from GLOBALCAN 2022.
Figure 2
Figure 2
Correlations between HDI and age-standardized morbidity and mortality in non-melanoma skin cancer (A) and melanoma of skin (B) based on data from GLOBALCAN 2022. The horizontal axis of the graph denotes the HDI levels. ASIR: Age-standardized incidence rates; ASMR: Age-standardized mortality rates; HDI: Human Development Index.
See this image and copyright information in PMC

References

    1. Hasan N Nadaf A Imran M Jiba U Sheikh A Almalki WH, et al. . Skin cancer: Understanding the journey of transformation from conventional to advanced treatment approaches. Mol Cancer 2023;22:168. doi: 10.1186/s12943-023-01854-3. - PMC - PubMed
    1. Khayyati Kohnehshahri M Sarkesh A Mohamed Khosroshahi L HajiEsmailPoor Z Aghebati-Maleki A Yousefi M, et al. . Current status of skin cancers with a focus on immunology and immunotherapy. Cancer Cell Int 2023;23:174. doi: 10.1186/s12935-023-03012-7. - PMC - PubMed
    1. Nakayama K. Growth and progression of melanoma and non-melanoma skin cancers regulated by ubiquitination. Pigment Cell Melanoma Res 2010;23:338–351. doi: 10.1111/j.1755-148X.2010.00692.x. - PubMed
    1. Lomas A, Leonardi-Bee J, Bath-Hextall F. A systematic review of worldwide incidence of non-melanoma skin cancer. Br J Dermatol 2012;166:1069–1080. doi: 10.1111/j.1365-2133.2012.10830.x. - PubMed
    1. Sung H Ferlay J Siegel RL Laversanne M Soerjomataram I Jemal A, et al. . Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin 2021;71:209–249. doi: 10.3322/caac.21660. - PubMed