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Review
. 2024 Nov 29;16(23):4131.
doi: 10.3390/nu16234131.

The Interactions Between Diet and Gut Microbiota in Preventing Gestational Diabetes Mellitus: A Narrative Review

Luiza-Andreea Beldie  1 , Cristina-Camelia Dica  1 , Maria Moța  2 , Bianca-Florentina Pirvu  1 , Marilena-Alexandra Burticală  1 , Adina Mitrea  3 , Diana Clenciu  3 , Ion Cristian Efrem  4 , Beatrice Elena Vladu  5 , Diana Cristina Protasiewicz Timofticiuc  1   6 , Maria Magdalena Roșu  6 , Theodora Claudia Gheonea  3 , Anca Maria Amzolini  7 , Eugen Moța  2 , Ionela Mihaela Vladu  3
Affiliations
Review

The Interactions Between Diet and Gut Microbiota in Preventing Gestational Diabetes Mellitus: A Narrative Review

Luiza-Andreea Beldie et al. Nutrients. .

Abstract

Recent studies have revealed that dysbiosis, defined as alterations in gut microbiota, plays an important role in the development and the progression of many non-communicable diseases, including metabolic disorders, such as type 2 diabetes mellitus and gestational diabetes mellitus (GDM). The high frequency of GDM makes this disorder an important public health issue, which needs to be addressed in order to reduce both the maternal and fetal complications that are frequently associated with this disease. The studies regarding the connections between gut dysbiosis and GDM are still in their early days, with new research continuously emerging. This narrative review seeks to outline the mechanisms through which a healthy diet that protects the gut microbiota is able to prevent the occurrence of GDM, thus providing medical nutritional therapeutic perspectives for the management of GDM.

Keywords: diet; gestational diabetes mellitus; gut microbiota; probiotics.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
VosViewer (version 1.6.19) bibliometric study of Web of Science papers studying the associations between gestational diabetes mellitus, gut microbiota and dietary factors.
Figure 2
Figure 2
The gut microbiome profile in healthy pregnancy versus gestational diabetes mellitus [30,31,34,35,36,37,38]. ↓ Decrease in the number of species, ↑ Increase in the number of species.
See this image and copyright information in PMC

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