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Editorial
. 2024 Dec 4;29(23):102739.
doi: 10.1016/j.jaccas.2024.102739.

Treating Familial Hypercholesterolemia: An Insistence on Persistence

Affiliations
Editorial

Treating Familial Hypercholesterolemia: An Insistence on Persistence

Jared A Spitz. JACC Case Rep. .
No abstract available

Keywords: familial hypercholesterolemia; lipid lowering therapy; prevention; statin intolerance; therapeutic inertia.

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Conflict of interest statement

The authors have reported that they have no relationships relevant to the contents of this paper to disclose.

Figures

None
Graphical abstract
Figure 1
Figure 1
Therapeutic Persistence Clinicians should engage patients in shared decision making to discuss therapeutic goals, available therapy, and adverse effects. This should be an ongoing conversation to ensure that personalized treatment of the right patients with the right medications to the right therapeutic goals is achieved.

Comment on

  • doi: 10.1016/j.jaccas.2024.102712

References

    1. Goldberg A.C., Hopkins P.N., Toth P.P., et al. Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J Clin Lipidol. 2011;5(3 suppl):S1–S8. doi: 10.1016/j.jacl.2011.04.003. - DOI - PubMed
    1. Lee C., Rivera-Valerio M., Bangash H., Prokop L., Kullo I.J. New case detection by cascade testing in familial hypercholesterolemia. Circ Genom Precis Med. 2019;12(11) doi: 10.1161/circgen.119.002723. - DOI - PMC - PubMed
    1. Dickson M.A., Zahavich L., Rush J., et al. Exploring barriers and facilitators to indirect cascade screening for familial hypercholesteraemia in a paediatric/parent population. CJC Pediatr Congenit Heart Dis. 2023;2(5):211. doi: 10.1016/j.cjcpc.2023.05.006. - DOI - PMC - PubMed
    1. Watts G.F., Gidding S.S., Hegele R.A., et al. International Atherosclerosis Society guidance for implementing best practice in the care of familial hypercholesterolaemia. Nat Rev Cardiol. 2023;20(12):845. doi: 10.1038/s41569-023-00892-0. - DOI - PubMed
    1. Lloyd-Jones D.M., Morris P.B., Ballantyne C.M., et al. 2022 ACC expert consensus decision pathway on the role of nonstatin therapies for LDL-cholesterol lowering in the management of atherosclerotic cardiovascular disease risk. J Am Coll Cardiol. 2022;80(14):1366. doi: 10.1016/j.jacc.2022.07.006. - DOI - PubMed

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