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. 2024 Dec 16;12(12):e70010.
doi: 10.1002/ccr3.70010. eCollection 2024 Dec.

Tongue Squamous Cell Carcinoma and Oral Lichen Planus: A Rare Case Report of a Pregnant Woman

David Moretti  1   2 , Joël Cucherousset  3 , Nadia Benlagha  4 , Ihsène Taïhi  1   5   6
Affiliations

Tongue Squamous Cell Carcinoma and Oral Lichen Planus: A Rare Case Report of a Pregnant Woman

David Moretti et al. Clin Case Rep. .

Abstract

Squamous cell carcinoma (SCC) of oral mucosa is increasingly affecting younger individuals, particularly in the tongue. SCC can develop from disorders like oral lichen planus (OLP). This case highlights the first known instance of OLP and SCC in a pregnant woman, suggesting hormonal changes and HPV as possible risk factors.

Keywords: oral lichen planus; precancerous condition; pregnant woman; squamous cells carcinoma; tongue neoplasms.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Clinical examination of the clinical case. (A) Squamous cell carcinoma on the lateral right side of the tongue, with a reticular lichen planus. (B) Reticular lichen planus on the lateral left side of the tongue, with no symptoms. (C) Reticular lichen planus on the cheek mucosa, with no symptoms.
FIGURE 2
FIGURE 2
Histological examination of the tumor after surgical glossectomy: Squamous cell carcinoma differentiated and infiltrant.
FIGURE 3
FIGURE 3
Follow‐up at 18 months after surgery (A) right side: Healing very well and no recurrence. (B) Left side: An erosion appeared on the reticular LPO, biopsy showed no epithelial dysplasia.
FIGURE 4
FIGURE 4
Timeline summarizing the main medical appointments of the patient presented in the clinical case. WA, weeks of amenorrhea.
See this image and copyright information in PMC

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