Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Dec 18;14(4):96244.
doi: 10.5500/wjt.v14.i4.96244.

Supervised vs home-based exercise program in kidney transplant recipients: A pilot pragmatic non-randomized study

Anna Crepaldi  1   2 , Giovanni Piva  1 , Nicola Lamberti  3 , Michele Felisatti  4 , Luca Pomidori  4 , Yuri Battaglia  5 , Fabio Manfredini  6 , Alda Storari  1 , Pablo Jesús López-Soto  7
Affiliations

Supervised vs home-based exercise program in kidney transplant recipients: A pilot pragmatic non-randomized study

Anna Crepaldi et al. World J Transplant. .

Abstract

Background: Although the benefits of exercise for kidney transplant recipients (KTRs) have been widely demonstrated, these patients experience several barriers in undertaking a structured exercise program in hospital and non-hospital facilities.

Aim: To compare the effects of a supervised moderate-intensity gym-based intervention with a home-based low-intensity walking program on exercise capacity in KTRs.

Methods: KTRs were asked to choose between two six-month programs. The first group performed a low-intensity interval walking intervention at home-based exercise intervention (HBex). The second group performed a supervised training program at an adapted physical activity gym (Sgym), including aerobic and resistance training. The outcomes, collected at baseline and at the end of the programs, included the 6-minute walking test, the peak oxygen consumption (VO2peak) during a treadmill test, the 5-time sit-to-stand test, and blood pressure.

Results: Seventeen patients agreed to participate and self-selected into the HBex (n = 9) and Sgym (n = 8) groups. Two patients in the Sgym group dropped out because of familial problems. At baseline, patients in the HBex group were significantly older and had lower walking distance, VO2peak, and lower limb strength. Primary outcome changes were significantly greater in the HBex group than in the Sgym group (52 ± 23 m vs 8 ± 34; P = 0.005). No other significant differences between groups were observed. Both groups improved most of the outcomes in the within-group comparisons, with significant variations in VO2 peak.

Conclusion: Six-month moderate-intensity supervised or low-intensity home-based training programs effectively improved exercise capacity in KTRs. Gym-based programs combine aerobic and resistance training; however, in-home walking may be proposed for frail KTRs.

Keywords: Exercise; Kidney disease; Nephrology; Training; Transplantation; Walking.

PubMed Disclaimer

Conflict of interest statement

Conflict-of-interest statement: All authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Flow diagram of the study. Hbex: Home-based exercise intervention; Sgym: Supervise training group.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Kovesdy CP. Epidemiology of chronic kidney disease: an update 2022. Kidney Int Suppl (2011) 2022;12:7–11. - PMC - PubMed
    1. Jang YS, Park YS, Kim H, Hurh K, Park EC, Jang SY. Association between sedentary behavior and chronic kidney disease in Korean adults. BMC Public Health. 2023;23:306. - PMC - PubMed
    1. Voora S, Adey DB. Management of Kidney Transplant Recipients by General Nephrologists: Core Curriculum 2019. Am J Kidney Dis. 2019;73:866–879. - PubMed
    1. GBD Chronic Kidney Disease Collaboration. Global, regional, and national burden of chronic kidney disease, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2020;395:709–733. - PMC - PubMed
    1. Czyżewski L, Sańko-Resmer J, Wyzgał J, Kurowski A. Assessment of health-related quality of life of patients after kidney transplantation in comparison with hemodialysis and peritoneal dialysis. Ann Transplant. 2014;19:576–585. - PubMed

LinkOut - more resources