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. 2024 Dec 18;17(12):2236-2242.
doi: 10.18240/ijo.2024.12.11. eCollection 2024.

Refraction difference value variations in children and adolescents with different refractive errors

Da-Wen Wu  1   2 , Ze-Yi Yang  1   2 , Yan Nie  1   2 , He-Ya Ye  1   2 , Liang Chen  1   2 , Long-Qian Liu  1   2 , Guo-Yuan Yang  1   2
Affiliations

Refraction difference value variations in children and adolescents with different refractive errors

Da-Wen Wu et al. Int J Ophthalmol. .

Abstract

Aim: To evaluate the refraction difference value (RDV) variations in children and adolescents with different refractive errors and analyze its correlation with refractive development.

Methods: Participants aged 4-16y with different refractive statuses (hyperopia, emmetropia, myopia) underwent comprehensive eye examinations, including spherical equivalent (SE) refraction, axial length (AL), total RDV (TRDV), and RDVs at various eccentricities (0°-15°, 15°-30°, 30°-45°) and quadrants (inferior, superior, nasal, temporal). Statistical analysis involved one-way ANOVA for group comparisons and Pearson correlation for examining relationships between SE/AL and RDVs. Paired t-tests compared quadrant-specific RDVs within groups.

Results: Significant difference was found in TRDV (P<0.001), RDV15°-30° (P=0.033), RDV30°-45° (P<0.001), RDV-inferior (RDV-I, P<0.001) and RDV-temporal (RDV-T, P<0.001) among hyperopia, emmetropia and myopia group. Pearson correlation analysis revealed a negative correlation of SE with TRDV (P=0.001), RDV30°-45° (P=0.004), RDV-I (P=0.047), and RDV-T (P<0.001). The differences between RDV-superior (RDV-S) and RDV-I were statistically significant in all groups (P<0.001 for all) and between RDV-T and RDV-nasal (RDV-N) were statistically significant in hyperopia group (P<0.001). Within the pre-myopic group, the analysis revealed a negative correlation of SE with RDV-I (P=0.009). Pearson correlation analysis revealed a positive correlation of AL with TRDV (P=0.036), RDV15°-30° (P=0.004), RDV30°-45° (P<0.001), RDV-S (P=0.003), RDV-I (P<0.001), RDV-T (P<0.001), RDV-N (P=0.022), while revealed a negative correlation of AL with RDV0-15° (P=0.018).

Conclusion: Our study indicates TRDV, RDV30°-45°, RDV-I, RDV-T may relate to refractive development, and a negative correlation between SE and RDV-I in pre-myopic children.

Keywords: adolescents; children; degrees of myopia; multispectral refractive topography; refraction difference value.

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Conflict of interest statement

Conflicts of Interest: Wu DW, None; Yang ZY, None; Nie Y, None; Ye HY, None; Chen L, None; Liu LQ, None; Yang GY, None.

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