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Review
. 2024 Nov 18;16(11):e73908.
doi: 10.7759/cureus.73908. eCollection 2024 Nov.

Spheno-Orbital Meningiomas: A Systematic Review of Treatment Modalities, Adjuvant Therapies, and Recurrence Risk

Injam Ibrahim Sulaiman  1 , Ali Hassan Baker  2 , Azhin Shafeeq  2 , Mustafa Ismail  3
Affiliations
Review

Spheno-Orbital Meningiomas: A Systematic Review of Treatment Modalities, Adjuvant Therapies, and Recurrence Risk

Injam Ibrahim Sulaiman et al. Cureus. .

Abstract

Spheno-orbital meningiomas (SOMs) are rare tumors that involve the sphenoid wing and orbit, leading to symptoms such as proptosis and vision loss. Their proximity to critical neurovascular structures complicates surgical resection, making management challenging. A systematic review of 22 paper series involving 1042 patients was conducted using PubMed and Scopus. Studies focused on SOM diagnosis, surgical techniques, recurrence rates, and the role of adjuvant therapies were analyzed. Proptosis and visual impairment were the most common symptoms. Gross total resection (GTR) reduced recurrence, but subtotal resection (STR) often led to higher recurrence, particularly in optic canal involvement. Minimally invasive approaches showed the potential to reduce morbidity. Adjuvant radiotherapy was effective in controlling tumor growth post-STR. SOM management requires a balance between tumor control and functional preservation. While GTR minimizes recurrence, STR with adjuvant radiotherapy is a viable alternative in challenging cases. Minimally invasive techniques offer promise, but further long-term studies are needed.

Keywords: adjuvant radiotherapy; minimally invasive surgery; orbital meningioma; proptosis; surgical resection.

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Conflict of interest statement

Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.

Figures

Figure 1
Figure 1. PRISMA flowchart of the included studies.
See this image and copyright information in PMC

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